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The first-line maintenance medication for ulcerative colitis in remission is mesalazine (also known as mesalamine or 5-ASA). [95] [96] For patients with active disease limited to the left colon (descending colon) or proctitis, mesalazine is also the first-line agent, and a combination of suppositories and oral mesalazine may be tried.
Management of ulcerative colitis involves first treating the acute symptoms of the disease, then maintaining remission. Ulcerative colitis is a form of colitis , a disease of the intestine , specifically the large intestine or colon , that includes characteristic ulcers , or open sores, in the colon.
Mesalazine, also known as mesalamine or 5-aminosalicylic acid (5-ASA), is a medication used to treat inflammatory bowel disease, including ulcerative colitis and Crohn's disease. [1] It is generally used for mildly to moderately severe disease. [1] It is taken by mouth or rectally. [1]
One such medication is mirikizumab — sold under the brand name Omvoh — which received Food and Drug Administration (FDA) approval for the treatment of ulcerative colitis in October 2023 ...
Budesonide assists in the induction of remission in people with active ulcerative colitis. [27] Budesonide is highly effective and recommended as the drug of choice in microscopic colitis, for induction and maintenance of remission, and for both the lymphocytic colitis and collagenous colitis forms. [28] [29]
Vedolizumab, sold under the brand name Entyvio, is a monoclonal antibody medication developed by Takeda Oncology for the treatment of ulcerative colitis and Crohn's disease. [5] It binds to integrin α 4 β 7 ( LPAM-1 , lymphocyte Peyer's patch adhesion molecule 1, a dimer of Integrin alpha-4 and Integrin beta-7 ), [ 5 ] [ 6 ] blocking the α 4 ...
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