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Ox gall (also spaced oxgall) is bile, also known as "gall", usually obtained from the gallbladder of cows, it is an ingredient in bile soap and mixed with alcohol and used as the wetting agent in paper marbling, engraving, lithography, and watercolor painting.
Bile acids are naturally synthesized from cholesterol in the liver and are conjugated with specific amino-acids, specifically taurine. Bear bile contains several bile acids including taurochenodeoxycholic acid, ursodeoxycholic acid, and chenodeoxycholic acid. [2]
In China, these are manufactured from cholic acid derived from bovine bile [3] combined with dry bovine bile powder, porcine ursodeoxycholic acid, taurine, bilirubin, cholesterol, etc. [4] Chinese regulations forbid the use of artificial calculus bovis in 42 drugs. [5]
It is a major constituent of bile and can be found in the large intestine, and accounts for up to 0.1% of total human body weight. Taurine is named after Latin taurus (cognate to Ancient Greek ταῦρος, taûros) meaning bull or ox, as it was first isolated from ox bile in 1827 by German scientists Friedrich Tiedemann and Leopold Gmelin. [2]
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a secondary bile acid, produced in humans and most other species from metabolism by intestinal bacteria.It is synthesized in the liver in some species, and was first identified in bile of bears of genus Ursus, from which its name derived. [8]
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Raw bile can sell for as much as US$24,000 per kg, about half the price of gold. [8] There is huge profitability in the trade of bile powder. In 2007, while the wholesale price of bile powder was approximately US$410 per kg in China, the retail price increased from 25 to 50 fold in South Korea, and to 80 fold in Japan, i.e. US$33,000 per kg. [50]
Bile (yellow material) in a liver biopsy stained with hematoxylin-eosin in a condition called cholestasis (setting of bile stasi). Bile (from Latin bilis), or gall, is a yellow-green/misty green fluid produced by the liver of most vertebrates that aids the digestion of lipids in the small intestine.
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