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Radiosensitivity is the relative susceptibility of cells, tissues, organs or organisms to the harmful effect of ionizing radiation. Cells types affected Cells ...
This figure illustrates the typical change in the relative radiosensitivity for a biological effect such as cell death when exposed to radiations of low ionizing density (e.g. x-rays). The hyperbolic relationship shown has a maximum OER of 2.70 for 100% oxygen (at 760 mmHg), with a half-range OER value at 4.2 mmHg or 0.55% of oxygen.
Zirkle et al. coined the term ‘linear energy transfer (LET)’ to be used in radiobiology for the stopping power, i.e. the energy loss per unit path length of a charged particle. The concept was introduced in the 1950s, at a time when the deployment of nuclear weapons and nuclear reactors spurred research on the biological effects of ...
The oxygen enhancement ratio (OER) or oxygen enhancement effect in radiobiology refers to the enhancement of therapeutic or detrimental effect of ionizing radiation due to the presence of oxygen. This so-called oxygen effect [ 1 ] is most notable when cells are exposed to an ionizing radiation dose .
Radiobiology (also known as radiation biology) is a field of clinical and basic medical sciences that involves the study of the action of radioactivity on biological systems. The controlled action of deleterious radioactivity on living systems is the basis of radiation therapy .
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Radioresistance is the level of ionizing radiation that organisms are able to withstand.. Ionizing-radiation-resistant organisms (IRRO) were defined as organisms for which the dose of acute ionizing radiation (IR) required to achieve 90% reduction (D10) is greater than 1,000 gray (Gy) [1]
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