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Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodium and T-type calcium channels , which leads to the suppression of neuronal hypersynchronization ...
In the United States, cenobamate is indicated for the treatment of partial-onset seizures in adults. [3]In the European Union, it is indicated for the adjunctive treatment of focal-onset seizures with or without secondary generalization in adults with epilepsy who have not been adequately controlled despite a history of treatment with at least two anti-epileptic medications.
People with epilepsy can have healthy pregnancies and healthy babies. However, proper planning and care is essential to minimize the risk of congenital malformations or adverse neurocognitive outcomes for the fetus while maintaining seizure control for the pregnant person with epilepsy.
Also known as “sundowner’s syndrome,” sundowning is a set of symptoms or behaviors that can be seen in some people with Alzheimer ... Dr. Kobylarz notes it can start as early as 1 p.m. for ...
Symptoms of toxicity include dizziness, vomiting, and blurry/double vision. The postpartum tapering plan may involve maintaining a slightly higher ASM dose than pre-pregnancy levels. The higher dose can protect the patient from the effects of sleep deprivation and added stressors during the postpartum period.
“Thirst can be mistaken for hunger pangs,” says Balls. “Dehydration symptoms include headache, fatigue, lightheadedness and difficulty concentrating, all of which resemble hunger symptoms.”
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Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...
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