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The squiggle notation was invented by Fritz Albert Lipmann, who first proposed ATP as the main energy transfer molecule of the cell, in 1941. [4] Lipmann's notation emphasizes the special nature of these bonds. [5] Stryer states: ATP is often called a high energy compound and its phosphoanhydride bonds are referred to as high-energy bonds.
Most useful ATP analogs cannot be hydrolyzed as ATP would be; instead, they trap the enzyme in a structure closely related to the ATP-bound state. Adenosine 5′-(γ-thiotriphosphate) is an extremely common ATP analog in which one of the gamma-phosphate oxygens is replaced by a sulfur atom; this anion is hydrolyzed at a dramatically slower rate ...
British Aerospace ATP, airliner; Airline transport pilot license; ATP Flight School, US; ATP (treaty), UN treaty that establishes standards for the international transport of perishable food; Aitape Airport, Papua New Guinea, IATA code; Anti-trespass panels, meant to deter pedestrians from walking on or adjacent to train tracks
ATP is a molecule found in and around living cells, and as such it gives a direct measure of biological concentration and health.ATP is quantified by measuring the light produced through its reaction with the naturally occurring firefly enzyme luciferase using a luminometer.
The ten-step catabolic pathway of glycolysis is the initial phase of free-energy release in the breakdown of glucose and can be split into two phases, the preparatory phase and payoff phase. ADP and phosphate are needed as precursors to synthesize ATP in the payoff reactions of the TCA cycle and oxidative phosphorylation mechanism. [ 4 ]
The ATP generated in this process is made by substrate-level phosphorylation, which does not require oxygen. Fermentation is less efficient at using the energy from glucose: only 2 ATP are produced per glucose, compared to the 38 ATP per glucose nominally produced by aerobic respiration. Glycolytic ATP, however, is produced more quickly.
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The adenylate energy charge is an index used to measure the energy status of biological cells.. ATP or Mg-ATP is the principal molecule for storing and transferring energy in the cell : it is used for biosynthetic pathways, maintenance of transmembrane gradients, movement, cell division, etc...
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