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Symptoms are thought to arise from transient abnormalities in the blood vessels of the brain. [1] In some cases, it may be associated with childbirth, vasoactive or illicit drug use, or complications of pregnancy. [1] If it occurs after delivery it may be referred to as postpartum cerebral angiopathy.
The narrowing of blood vessels leads to an increase in peripheral resistance, thereby elevating blood pressure. While vasoconstriction is a normal and essential regulatory mechanism for maintaining blood pressure and redistributing blood flow during various physiological processes, its dysregulation can contribute to pathological conditions.
Hyperventilation is still used if ICP is resistant to other methods of control, or there are signs of brain herniation, because the damage herniation can cause is so severe that it may be worthwhile to constrict blood vessels even if doing so reduces blood flow. ICP can also be lowered by raising the head of the bed, improving venous drainage.
Most side effects are direct consequences of the vasodilation and the resultant low blood pressure. They include headache ("nitrate headache") resulting from the widening of blood vessels in the brain, reflex tachycardia (fast heart rate), flush, dizziness, nausea and vomiting. These effects usually subside after a few days if the treatment is ...
Vascular resistance is the resistance that must be overcome for blood to flow through the circulatory system.The resistance offered by the systemic circulation is known as the systemic vascular resistance or may sometimes be called by another term total peripheral resistance, while the resistance caused by the pulmonary circulation is known as the pulmonary vascular resistance.
Like most pharmacological therapeutic options, there are risks that should be considered. For these drugs in particular, vasodilation can be associated with some adverse effects which might include orthostatic hypotension, reflex tachycardia, headaches and palpitations. Tolerance may also develop over time due compensatory response of the body ...
Neurogenic shock is diagnosed based on a person's symptoms and blood pressure levels. Neurogenic shock's presentation includes: [7] [8] - warm and pink skin - labored breathing - low blood pressure - dizziness - anxiety - history of trauma to head or upper spine. - if the injury is to the head or neck, hoarseness or difficulty swallowing may occur.
Infarction occurs as a result of prolonged ischemia, which is the insufficient supply of oxygen and nutrition to an area of tissue due to a disruption in blood supply. [5] The blood vessel supplying the affected area of tissue may be blocked due to an obstruction in the vessel (e.g., an arterial embolus, thrombus, or atherosclerotic plaque ...