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The cell survival curve is a curve often used in radiobiology that represents the relationship between the amount of cells retaining reproductive capabilities and the absorbed dose of radiation from said cells.
This figure illustrates the typical change in the relative radiosensitivity for a biological effect such as cell death when exposed to radiations of low ionizing density (e.g. x-rays). The hyperbolic relationship shown has a maximum OER of 2.70 for 100% oxygen (at 760 mmHg), with a half-range OER value at 4.2 mmHg or 0.55% of oxygen.
Data for CHO-K1 cell line irradiated by photons (blue curve) and by carbon ions (red curve). ... corresponding to some common survival rate. ... used in radiobiology ...
In the graph to the right, called a cell survival curve, the dose vs. surviving fraction have been drawn for a hypothetical group of cells with and without a rest time for the cells to recover. Other than the recovery time partway through the irradiation, the cells would have been treated identically.
Radiation with higher LET and higher relative biological effectiveness (RBE) have a lower OER in mammalian cell tissues. [2] The value of the maximum OER varies from about 1–4. The maximum OER ranges from about 2–4 for low-LET radiations such as X-rays, beta particles and gamma rays, whereas the OER is unity for high-LET radiations such as ...
Radiobiology (also known as radiation biology, and uncommonly as actinobiology) is a field of clinical and basic medical sciences that involves the study of the effects of ionizing radiation on living things, in particular health effects of radiation.
Radiobiology (also known as radiation biology) is a field of clinical and basic medical sciences that involves the study of the action of radioactivity on biological systems. The controlled action of deleterious radioactivity on living systems is the basis of radiation therapy .
A clonogenic assay is a cell biology technique for studying the effectiveness of specific agents on the survival and proliferation of cells. It is frequently used in cancer research laboratories to determine the effect of drugs or radiation on proliferating tumor cells [1] as well as for titration of Cell-killing Particles (CKPs) in virus stocks. [2]