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When the dosage is equal to 1/A, S = 0.37 (or e^-1). For this reason, D0 is often called the mean lethal dose, the dose that creates one lethal event per target on average. Curved cell survival curves (cells exposed to low-LET radiation) show two distinct regions: low dose regions and high dose regions.
Cyclin B is a member of the cyclin family. Cyclin B is a mitotic cyclin. The amount of cyclin B (which binds to Cdk1) and the activity of the cyclin B-Cdk complex rise through the cell cycle [2] until mitosis, where they fall abruptly due to degradation of cyclin B (Cdk1 is constitutively present). [3]
Tiếng Việt; 中文; Edit links ... Pages in category "Curves" The following 118 pages are in this category, out of 118 total. ... Cell survival curve; Center of ...
Overview of signal transduction pathways involved in apoptosis. Cell death is the event of a biological cell ceasing to carry out its functions. This may be the result of the natural process of old cells dying and being replaced by new ones, as in programmed cell death, or may result from factors such as diseases, localized injury, or the death of the organism of which the cells are part.
A cell undergoing apoptosis shows a series of characteristic morphological changes. Early alterations include: Cell shrinkage and rounding occur because of the retraction of lamellipodia and the breakdown of the proteinaceous cytoskeleton by caspases. [56] The cytoplasm appears dense, and the organelles appear tightly packed. [citation needed]
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Cell growth refers to an increase in the total mass of a cell, including both cytoplasmic, nuclear and organelle volume. [1] Cell growth occurs when the overall rate of cellular biosynthesis (production of biomolecules or anabolism) is greater than the overall rate of cellular degradation (the destruction of biomolecules via the proteasome, lysosome or autophagy, or catabolism).
The survival function is also known as the survivor function [2] or reliability function. [3] The term reliability function is common in engineering while the term survival function is used in a broader range of applications, including human mortality. The survival function is the complementary cumulative distribution function of the lifetime ...