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Most human tissue and organ transplants are allografts. Due to the genetic difference between the organ and the recipient, the recipient's immune system will identify the organ as foreign and attempt to destroy it, causing transplant rejection. The risk of transplant rejection can be estimated by measuring the panel-reactive antibody level.
Kidney transplantation is the organ transplant of a kidney in a patient with end-stage renal disease. Kidney transplantation is typically classified as deceased-donor (formerly known as cadaveric) or living-donor transplantation depending on the source of the recipient organ.
The National Organ Transplant Act (NOTA) of 1984 is an Act of the United States Congress that created the framework for the organ transplant system in the country. [1] The act provided clarity on the property rights of human organs obtained from deceased individuals and established a public-private partnership known as Organ Procurement and Transplantation Network (OPTN).
If the organ donor is human, most countries require that the donor be legally dead for consideration of organ transplantation (e.g. cardiac death or brain death). For some organs, a living donor can be the source of the organ. For example, living donors can donate one kidney or part of their liver to a well-matched recipient. [2]
A beating heart awaiting transplant. American medical researcher Simon Flexner was one of the first people to mention the possibility of heart transplantation. In 1907, he wrote the paper "Tendencies in Pathology," in which he said that it would be possible one day by surgery to replace diseased human organs – including arteries, stomach, kidneys and heart.
Even though a record 41,000 organ transplants were conducted in the U.S. last year, ... If science advances to the point where animal organs are a readily available option for human transplants ...
The lack of available organs for transplant is an urgent public health issue.” ... also a ‘commanded obligation’ which saves human lives.” In Catholicism, organ donation is viewed as “an ...
Organ trade (also known as the blood market or the red market) is the trading of human organs, tissues, or other body products, usually for transplantation. [1] [2] According to the World Health Organization (WHO), organ trade is a commercial transplantation where there is a profit, or transplantations that occur outside of national medical systems.