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Saponification is a process of cleaving esters into carboxylate salts and alcohols by the action of aqueous alkali.Typically aqueous sodium hydroxide solutions are used. [1] [2] It is an important type of alkaline hydrolysis.
Example of saponification reaction of a triglyceride molecule (left) with potassium hydroxide (KOH) yielding glycerol (purple) and salts of fatty acids ().. Saponification value or saponification number (SV or SN) represents the number of milligrams of potassium hydroxide (KOH) or sodium hydroxide (NaOH) required to saponify one gram of fat under the conditions specified.
Adipocere was first described by Sir Thomas Browne in his discourse Hydriotaphia, Urn Burial (1658): [4]. In a Hydropicall body ten years buried in a Church-yard, we met with a fat concretion, where the nitre of the Earth, and the salt and lixivious liquor of the body, had coagulated large lumps of fat, into the consistence of the hardest castile-soap: wherof part remaineth with us.
Alkaline hydrolysis of esters is also known as saponification. A base such as sodium hydroxide is required in stochiometric amounts. Unlike acid-catalyzed ester hydrolysis, it is not an equilibrium reaction and proceeds to completion.
This article was reviewed by Craig Primack, MD, FACP, FAAP, FOMA. Once opened, compounded semaglutide typically lasts 28 days in the fridge. Compounded semaglutide, which contains the same active ...
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A saponifiable lipid is part of the ester functional group. They are made up of long chain carboxylic (of fatty) acids connected to an alcoholic functional group through the ester linkage which can undergo a saponification reaction.
Binge drinking is defined as the amount of alcohol it takes to raise a person’s blood-alcohol concentration level to 0.08, the legal definition of being intoxicated in most states.