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An experimental design is the laying out of a detailed experimental plan in advance of doing the experiment. Some of the following topics have already been discussed in the principles of experimental design section: How many factors does the design have, and are the levels of these factors fixed or random?
In 1954, the Universities Federation for Animal Welfare (UFAW) decided to sponsor systematic research on the progress of humane techniques in the laboratory. [2] In October of that year, William Russell, described as a brilliant young zoologist who happened to be also a psychologist and a classical scholar, and Rex Burch, a microbiologist, were appointed to inaugurate a systematic study of ...
The Design of Experiments is a 1935 book by the English statistician Ronald Fisher about the design of experiments and is considered a foundational work in experimental design. [1] [2] [3] Among other contributions, the book introduced the concept of the null hypothesis in the context of the lady tasting tea experiment. [4]
For example, agricultural research frequently uses randomized experiments (e.g., to test the comparative effectiveness of different fertilizers), while experimental economics often involves experimental tests of theorized human behaviors without relying on random assignment of individuals to treatment and control conditions.
In natural and social science research, a protocol is most commonly a predefined procedural method in the design and implementation of an experiment.Protocols are written whenever it is desirable to standardize a laboratory method to ensure successful replication of results by others in the same laboratory or by other laboratories.
Much of this research has been associated with the subdiscipline of system identification. [30] In computational optimal control , D. Judin & A. Nemirovskii and Boris Polyak has described methods that are more efficient than the ( Armijo-style ) step-size rules introduced by G. E. P. Box in response-surface methodology .
Natural experiments are employed as study designs when controlled experimentation is extremely difficult to implement or unethical, such as in several research areas addressed by epidemiology (like evaluating the health impact of varying degrees of exposure to ionizing radiation in people living near Hiroshima at the time of the atomic blast [3 ...
This increases the speed and efficiency of gathering experimental results and reduces the costs of implementing the experiment. Another cutting-edge technique in field experiments is the use of the multi armed bandit design, [ 11 ] including similar adaptive designs on experiments with variable outcomes and variable treatments over time.