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  2. Lean (drug) - Wikipedia

    en.wikipedia.org/wiki/Lean_(drug)

    Lean or purple drank (known by numerous local and street names) is a polysubstance drink used as a recreational drug.It is prepared by mixing prescription-grade cough or cold syrup containing an opioid drug and an anti-histamine drug with a soft drink and sometimes hard candy.

  3. Oxycodone - Wikipedia

    en.wikipedia.org/wiki/Oxycodone

    Oxycodone, a semi-synthetic opioid, is a highly selective full agonist of the μ-opioid receptor (MOR). [41] [42] This is the main biological target of the endogenous opioid neuropeptide β-endorphin. [19] Oxycodone has low affinity for the δ-opioid receptor (DOR) and the κ-opioid receptor (KOR), where it is an agonist similarly.

  4. Detoxification (alternative medicine) - Wikipedia

    en.wikipedia.org/wiki/Detoxification...

    Detoxification (often shortened to detox and sometimes called body cleansing) is a type of alternative-medicine treatment which aims to rid the body of unspecified "toxins" – substances that proponents claim accumulate in the body over time and have undesirable short-term or long-term effects on individual health.

  5. Oxycodone/naloxone - Wikipedia

    en.wikipedia.org/wiki/Oxycodone/naloxone

    Oxycodone/naloxone was released in 2014 in the United States, [5] in 2006 in Germany, and has been available in some other European countries since 2009. In the United Kingdom, the 10 mg oxycodone / 5 mg naloxone and 20 mg / 10 mg strengths were approved in December 2008, and the 40 mg / 20 mg and 5 mg / 10 mg strengths received approval in ...

  6. Oxymorphone - Wikipedia

    en.wikipedia.org/wiki/Oxymorphone

    Oxymorphone (sold under the brand names Numorphan and Opana among others) is a highly potent opioid analgesic indicated for treatment of severe pain. Pain relief after injection begins after about 5–10 minutes, after oral administration it begins after about 30 minutes, and lasts about 3–4 hours for immediate-release tablets and 12 hours for extended-release tablets. [6]

  7. 'Call Her Daddy' host Alex Cooper announces new drink ... - AOL

    www.aol.com/call-her-daddy-host-alex-202918405.html

    How to buy Unwell Hydration. Unwell Hydration will be available exclusively in stores and online at Target starting Jan. 1, 2025, for around $2.49 per 16.9 fl.oz bottle and $14.99 for an 8-pack.

  8. Opioid use disorder - Wikipedia

    en.wikipedia.org/wiki/Opioid_use_disorder

    Men are at higher risk for opioid use and dependency than women, [205] [206] and men also account for more opioid overdoses than women, although this gap is closing. [205] Women are more likely to be prescribed pain relievers, be given higher doses, use them for longer durations, and become dependent upon them faster. [207]

  9. Naltrexone - Wikipedia

    en.wikipedia.org/wiki/Naltrexone

    Naltrexone, sold under the brand name Revia among others, is a medication primarily used to manage alcohol use or opioid use disorder by reducing cravings and feelings of euphoria associated with substance use disorder. [8]

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