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Amlodipine was patented in 1982, and approved for medical use in 1990. [12] It is on the World Health Organization's List of Essential Medicines. [13] It is available as a generic medication. [10] [14] In 2022, it was the fifth most commonly prescribed medication in the United States, with more than 70 million prescriptions.
The book was distributed for free to all licensed medical doctors in America; only drugs which drug manufacturers paid to appear, appeared in the PDR, and no generic drugs were listed. The 71st Edition, published in 2017, was the final hardcover edition, weighed in at 4.6 pounds (2.1 kg) and contained information on over 1,000 drugs. [1]
Amlodipine/olmesartan, sold under the brand name Azor, among others is a fixed-dose combination medication used to treat high blood pressure. [5] It contains amlodipine , as the besilate, a dihydropyridine calcium channel blocker , and olmesartan medoxomil , an angiotensin II receptor blocker .
In 2007 the company filed its first ANDA for drug Amlodipine which was approved in 2009. [3] Alkem has developed a portfolio of 705 branded generic drugs, with 13 of the brands featured among the top 300 brands in India for the fiscal year 2015 and a portfolio of 705 brands in India in the six months ended 30 September 2015.
Amlodipine/benazepril, sold under the brand name Lotrel among others, is a fixed-dose combination medication used to treat high blood pressure. [1] It is a combination of amlodipine , as the besilate, a calcium channel blocker , and benazepril , an angiotensin converting enzyme inhibitor . [ 1 ]
The combination was approved for medical use in the European Union in January 2007, [3] and in the United States in June 2007. [8] The combination is also available with hydrochlorothiazide. [9] [10] It was approved for medical use in the United States in April 2009, [11] and in the European Union in November 2009. [12] [13] [14]
A new pill combining low doses of three different anti-hypertensive medications surpassed the standard care for high blood pressure using one anti-hypertensive drug, a new study showed.
Sandoz Group AG is a Swiss company that focuses on generic pharmaceuticals and biosimilars. [4] Prior to October 2023, it was part of a division of Novartis that was established in 2003, when Novartis united all of its generics businesses under the name Sandoz.