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Lipoic acid (LA), also known as α-lipoic acid, alpha-lipoic acid (ALA) and thioctic acid, is an organosulfur compound derived from caprylic acid (octanoic acid). [3] ALA, which is made in animals normally, is essential for aerobic metabolism. It is also available as a dietary supplement or pharmaceutical drug in some countries.
Alpha lipoic acid (ALA) with benfotiamine is a proposed pathogenic treatment for painful diabetic neuropathy only. [119] The results of two systematic reviews state that oral ALA produced no clinically significant benefit, intravenous ALA administered over three weeks may improve symptoms and that long-term treatment has not been investigated ...
A 2007 review of studies found that injected administration of alpha lipoic acid (ALA) was found to reduce the various symptoms of peripheral diabetic neuropathy. [73]
Certain vitamins help support brain health. Experts share the nutrient-rich foods to eat for a healthy brain and if supplements for brain health are worth it.
Aldixyl®: In 2016, based on studies developed in recent years in the field of adrenoleukodystrophy and adrenomyelouropathy, a mixture was developed that adds to GTO, GTE and CLA, a mixture of powerful antioxidants at high dosages containing alpha lipoic acid (ALA), reduced L- glutathione and Vitamin E (α- tocopherol).
Aspirin "weakens the stomach's protective lining against stomach acid, making the stomach and intestines more vulnerable to ulcers, which can bleed," according to Harvard Health.
Benfotiamine has been studied in laboratory models of diabetic retinopathy, neuropathy, and nephropathy. [10] A 2021 review of its use for diabetic polyneuropathy described two clinical trials which showed improvements in neuropathic pain and neuropathic symptoms scores, the latter of which showed a dose-response effect. [4]
Alpha lipoic acid (ALA) is an antioxidant that is made naturally by human cells. [50] It can also be administered in capsules or can be found in foods such as red meat, organ meats, and yeast. [50] Like other antioxidants, it functions by ridding the body of harmful free radicals that can cause damage to tissues and organs. [50]
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