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NMT is known to act as a potent serotonin 5-HT 2A receptor full agonist (EC 50 Tooltip half-maximal effective concentration = 50.7 nM; E max Tooltip maximal efficacy = 96%). [5] It has been reported to be inactive in activating the β-arrestin pathway of the receptor and hence appears to be a biased agonist of the serotonin 5-HT 2A receptor. [5]
Trade discounts are most frequent in industries where retailers hold the majority of the power in the distribution channel (referred to as channel captains). Trade discounts are given to try to increase the volume of sales being made by the supplier. The discount described as trade rate discount is sometimes called "trade discount".
Conversion and its related terms yield and selectivity are important terms in chemical reaction engineering.They are described as ratios of how much of a reactant has reacted (X — conversion, normally between zero and one), how much of a desired product was formed (Y — yield, normally also between zero and one) and how much desired product was formed in ratio to the undesired product(s) (S ...
In economics, a discount function is used in economic models to describe the weights placed on rewards received at different points in time. For example, if time is discrete and utility is time-separable, with the discount function f(t) having a negative first derivative and with c t (or c(t) in continuous time) defined as consumption at time t, total utility from an infinite stream of ...
C 5 H 8 O 2: gamma-Valerolactone: C 5 H 9 NO 3-Dimethylaminoacrolein: 927-63-9 C 5 H 9 NO 2: allylglycine: C 5 H 9 NO 2: proline Pro: 147-85-3 C 5 H 9 NO 4: glutamic acid Glu: 56-86-0 C 5 H 10: cyclopentane: 287-92-3 C 5 H 10 N 2 O 3: glutamine Gln: 56-85-9 C 5 H 10 O 2: pivalic acid: C 5 H 10 O 2: valeric acid: C 5 H 10 O 2: 3-Methylbutanoic ...
At date t = 1, this investment opportunity is considered favorable; hence, this function is: −δC + δ^2 B > 0. Now consider from the perspective of date t = 2, this investment opportunity is still viewed as favorable given −C + δB > 0. To view this mathematically, observe that the new expression is the old expression multiplied by 1/δ.
Theoretical chemistry requires quantities from core physics, such as time, volume, temperature, and pressure.But the highly quantitative nature of physical chemistry, in a more specialized way than core physics, uses molar amounts of substance rather than simply counting numbers; this leads to the specialized definitions in this article.
Ligand efficiency is a measurement of the binding energy per atom of a ligand to its binding partner, such as a receptor or enzyme. [1]Ligand efficiency is used in drug discovery research programs to assist in narrowing focus to lead compounds with optimal combinations of physicochemical properties and pharmacological properties.