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Ulcers are most common on the lower limbs (roughly 62% of ulcers globally) and upper limbs (24%), but can also be found on the trunk (9%), head or neck (3%), or genitals (less than 1%). [ 8 ] The World Health Organization classifies Buruli ulcer into three categories depending on the severity of its symptoms.
A 2004 WHO resolution "called for increasing surveillance and control, and for intensified research to develop tools to diagnose, treat and prevent" Buruli ulcer. [4] In 2009, a strategy to promote early detection and provide wider access to antibiotics was adopted. [ 6 ]
The Evening News: state-owned The Finder Newspaper: news from Ghana and Africa, politics, entertainment, world, health, business and sports Today Newspaper: North Ridge, Accra 2007 Ghana Sports Publications Limited w.todaygh.com: private Free Press: private The Gazette Newspaper: weekly newspaper The Ghanaian Chronicle [3] Accra 1996 [4 ...
The bacteria can infect humans and some other animals, causing persistent open wounds called Buruli ulcer. M. ulcerans is closely related to Mycobacterium marinum , from which it evolved around one million years ago, and more distantly to the mycobacteria which cause tuberculosis and leprosy .
The prevalence of Buruli ulcer is unknown. [18] The risk of mortality is low, although secondary infections can be lethal. [35] Morbidity takes the form of deformity, disability, and skin lesions, which can be prevented through early treatment with antibiotics and surgery. [35] It is found in Africa, Asia, Australia, [36] and Latin America. [37]
Buruli ulcer is an infectious disease characterized by the development of painless open wounds. The disease largely occurs in sub-Saharan Africa and Australia, generally in rural areas near slow-moving or stagnant water. The first sign of infection is a small painless nodule or area of swelling, typically on the arms or legs.
The disease often goes untreated because of the scarcity of medical treatment in the countries in which it is found. In addition, the painless genital ulcers can be mistaken for syphilis. [5] The ulcers ultimately progress to destruction of internal and external tissue, with extensive leakage of mucus and blood from the highly vascular lesions.
English: From source: "Characteristic histopathological features of tissue samples taken before start of antibiotic treatment. Histological sections were stained either with Haematoxylin-Eosin (HE) (A, C–E), Ziehl-Neelsen (counterstain methylenblue) (ZN) (B) ..