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Magnesium is absorbed orally at about 30% bioavailability from any water soluble salt, such as magnesium chloride or magnesium citrate. The citrate is the least expensive soluble (high bioavailability) oral magnesium salt available in supplements, with 100 mg and 200 mg magnesium typically contained per capsule, tablet or 50 mg/mL in solution. [26]
The Recommended Dietary Allowance (RDA) for magnesium is 400-420 mg for men, 310-320 mg for women, 350-360 mg for pregnant women, and 310-320 for breastfeeding women. But that may not be enough.
Common side effects include low blood pressure, skin flushing, and low blood calcium. [1] Other side effects may include vomiting, muscle weakness, and decreased breathing. [4] While there is evidence that use during pregnancy may harm the baby, the benefits in certain conditions are greater than the risks. [5]
Magnesium aspartate is a compound formed by the combination of the divalent magnesium cation (Mg2+) and the dicarboxylic amino acid aspartate (C4H6NO4-). [1] The chemical formula for this compound is Mg(C4H6NO4)2. [7] The structure of magnesium aspartate consists of a central magnesium ion that is chelated, or bound, by two aspartate anions.
Magnesium glycinate, also known as magnesium diglycinate or magnesium bisglycinate, is the magnesium salt of glycine (one magnesium and two glycine molecules), and is sold as a dietary supplement. [ 1 ] [ 2 ] It contains 14.1% elemental magnesium by mass.
The most common symptom of excess oral magnesium intake is diarrhea. Supplements based on amino acid chelates (such as glycinate, lysinate etc.) are much better-tolerated by the digestive system and do not have the side-effects of the older compounds used, while sustained-release dietary supplements prevent the occurrence of diarrhea.
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