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7-Methylxanthine (7-MX), also known as heteroxanthine, is an active metabolite of caffeine (1,3,7-trimethylxanthine) and theobromine (3,7-dimethylxanthine). [1] [2] It is a non-selective antagonist of the adenosine receptors. [1] [2] The compound may slow the progression of myopia (nearsightedness).
The legs and face are the most common sites involved, although cellulitis can occur on any part of the body. [1] The leg is typically affected following a break in the skin. [1] Other risk factors include obesity, leg swelling, and old age. [1] For facial infections, a break in the skin beforehand is not usually the case. [1]
Methylxanthines are chemical compounds which are derivatives of xanthine with one or more methyl groups, including: One methyl group: 1-Methylxanthine; 3-Methylxanthine; 7-Methylxanthine; Two methyl groups: Theophylline (1,3-dimethylxanthine) Paraxanthine (1,7-dimethylxanthine) Theobromine (3,7-dimethylxanthine) Three methyl groups:
A recent meta-analysis of 24 epidemiological studies on the prevalence of OSA in the general population aged 18 and older revealed that for ≥ 5 apnea events per hour, OSA prevalence ranged from 9% to 38%, specifically ranging from 13% to 33% in men and 6% to 19% in women, while in the population aged 65 and older, OSA prevalence was as high ...
Sleep apnea is somewhat more common in men than women, roughly a 2:1 ratio of men to women, and in general more people are likely to have it with older age and obesity. Other risk factors include being overweight, [19] a family history of the condition, allergies, and enlarged tonsils. [6]
The syndrome is often associated with obstructive sleep apnea (OSA), which causes periods of absent or reduced breathing in sleep, resulting in many partial awakenings during the night and sleepiness during the day. [1] The disease puts strain on the heart, which may lead to heart failure and leg swelling.
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Erysipelas (/ ˌ ɛ r ə ˈ s ɪ p ə l ə s /) is a relatively common bacterial infection of the superficial layer of the skin (upper dermis), extending to the superficial lymphatic vessels within the skin, characterized by a raised, well-defined, tender, bright red rash, typically on the face or legs, but which can occur anywhere on the skin.