Search results
Results from the WOW.Com Content Network
Tumor stroma and extracellular matrix in hypoxia. Tumor hypoxia is the situation where tumor cells have been deprived of oxygen.As a tumor grows, it rapidly outgrows its blood supply, leaving portions of the tumor with regions where the oxygen concentration is significantly lower than in healthy tissues.
Tissue hypoxia refers to low levels of oxygen in the tissues of the body and the term hypoxia is a general term for low levels of oxygen. [2] Hypoxemia is usually caused by pulmonary disease whereas tissue oxygenation requires additionally adequate circulation of blood and perfusion of tissue to meet metabolic demands. [4]
Hypoxia is also involved in the pathogenesis of some common and severe pathologies. [81] The most common causes of death in an aging population include myocardial infarction, stroke and cancer. These diseases share a common feature that limitation of oxygen availability contributes to the development of the pathology.
Generalized hypoxia is a medical condition in which the tissues of the body are deprived of the necessary levels of oxygen due to an insufficient supply of oxygen, which may be due to the composition or pressure of the breathing gas, decreased lung ventilation, or respiratory disease, any of which may cause a lower than normal oxygen content in the arterial blood, and consequently a reduced ...
Leukocytes. Symptomatic Hyperleukocytosis (Leukostasis) is defined by a tremendously high blast cell count along with symptoms of decreased tissue perfusion.Leukostasis is associated with people who have bone and blood disorders and is very common among people with acute myeloid leukemia or chronic myeloid leukemia.
Histotoxic hypoxia, the inability of cells to take up or use oxygen from the bloodstream; Anemic hypoxia, Blood is not able to take sufficient amount of oxygen due to Anemia; Hypoxemic hypoxia or hypoxemia, a deficiency of oxygen in arterial blood; Hypoxic hypoxia, a result of insufficient oxygen available to the lungs
An SaO 2 (arterial oxygen saturation) value below 90% causes hypoxia (which can also be caused by anemia). Hypoxia due to low SaO 2 is indicated by cyanosis, but oxygen saturation does not directly reflect tissue oxygenation. The affinity of hemoglobin to oxygen may impair or enhance oxygen release at the tissue level.
Hyperoxia is the opposite of hypoxia; hyperoxia refers to a state in which oxygen supply to the tissues is excessive, while hypoxia refers to a state in which oxygen supply is insufficient. [ 2 ] Supplementary oxygen administration is widely used in emergency and intensive care medicine and can be life-saving in critical conditions, but too ...