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Betahistine was once believed to have some positive effects in the treatment of Ménière's disease and vertigo, [3] but more recent evidence casts doubt on its efficacy. [4] [5] Studies of the use of betahistine have shown a reduction in symptoms of vertigo and, to a lesser extent, tinnitus, but conclusive evidence is lacking at present.
A histamine agonist is a drug which causes increased activity at one or more of the four histamine receptor subtypes.. H 1 agonists promote wakefulness. [1]H 2: Betazole and Impromidine are examples of agonists used in diagnostics to increase histamine.
An H 3 receptor antagonist is a type of antihistaminic drug used to block the action of histamine at H 3 receptors.. Unlike the H 1 and H 2 receptors which have primarily peripheral actions, but cause sedation if they are blocked in the brain, H 3 receptors are primarily found in the brain and are inhibitory autoreceptors located on histaminergic nerve terminals, which modulate the release of ...
The most common adverse effect is sedation; this "side-effect" is utilized in many OTC sleeping-aid preparations. Other common adverse effects in first-generation H 1 -antihistamines include dizziness, tinnitus , blurred vision, euphoria , incoordination, anxiety , increased appetite leading to weight gain , insomnia , tremor, nausea and ...
Cyclizine, sold under a number of brand names, is a medication used to treat and prevent nausea, vomiting and dizziness due to motion sickness or vertigo. [2] It may also be used for nausea after general anaesthesia or that which developed from opioid use. [2] [3] It is taken by mouth, in the rectum, or injected into a vein. [3] [4]
Meclizine, sold under the brand name Bonine, among others, is an antihistamine used to treat motion sickness and dizziness . [3] It is taken by mouth. [3] Effects generally begin in an hour and last for up to a day. [3] Common side effects include sleepiness and dry mouth. [3] Serious side effects may include allergic reactions. [3]
Cinnarizine is an antihistamine and calcium channel blocker of the diphenylmethylpiperazine group. [5] It is prescribed for nausea and vomiting due to motion sickness [6] or other sources such as chemotherapy, [7] vertigo, [8] or Ménière's disease. [9]
Hydroxyzine works by blocking the effects of histamine. [9] It is a first-generation antihistamine in the piperazine family of chemicals. [8] [4] Common side effects include sleepiness, headache, and dry mouth. [8] [9] Serious side effects may include QT prolongation. [9] It is unclear if use during pregnancy or breastfeeding is safe. [8]
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