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Generic sildenafil (and brand-name Viagra) is a medication for the treatment of ED, Raynaud’s phenomenon, and pulmonary arterial hypertension. To understand how Viagra works, we need to look at ...
Sildenafil's brand name, Viagra, is widely recognized in popular culture, and the drug's association with treating erectile dysfunction has led to its recreational use. [33] The reasons behind such use include the belief that the drug increases libido, improves sexual performance, [ 33 ] or permanently increases penis size. [ 34 ]
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
For example, in clinical trials of sildenafil, 28 percent of men reported headache (by far the most common side effect) at a dosage of 100mg, compared to just 16 percent of men who used 25mg and ...
Viagra’s main ingredient sildenafil is part of a class of drugs referred to as PDE5 inhibitors, which (unlike non-prescription supplements) are approved by the FDA for the treatment of ED.
Half of the sample pool were treated with dapoxetine 60 mg plus tadalafil 20 mg; the other half were treated with dapoxetine 60 mg plus sildenafil 100 mg. These plasma samples were then analyzed using liquid chromatography-tandem mass spectrometry. The results showed that dapoxetine does not alter the pharmacokinetic of tadalafil or sildenafil.
That “Viagra hangover” might actually be a headache from Viagra, and it’s a common side effect of this and other medications for ED. Skip to main content. Subscriptions ...
"A Case Report of Sildenafil-Induced Cyanopsia" (2021): Published in the Korean Journal of Clinical Pharmacy, this study explored the neurological impact of sildenafil on the visual system. Using advanced imaging techniques, researchers identified altered rod and cone photoreceptor activity, contributing to the perception of blue-tinted vision.