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Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [10] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [10] It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. [10]
The Monthly Index of Medical Specialities or MIMS is a pharmaceutical prescribing reference guide published in the United Kingdom since 1959 by Haymarket Media Group.MIMS is also published internationally by various organisations, including in Australia, New Zealand, China, Hong Kong, India, Indonesia, Japan, Korea, Malaysia, Myanmar, the Philippines, Singapore, Thailand, and Vietnam.
The book was distributed for free to all licensed medical doctors in America; only drugs which drug manufacturers paid to appear, appeared in the PDR, and no generic drugs were listed. The 71st Edition, published in 2017, was the final hardcover edition, weighed in at 4.6 pounds (2.1 kg) and contained information on over 1,000 drugs. [ 1 ]
Logo of F.A. Davis Co., taken from its 1892 edition of Dr. Richard Krafft-Ebbing's classic treatise, Psychopathia Sexualis Frank Allston Davis (1850–1917) was an American businessman and entrepreneur who founded the F.A. Davis Company, a medical publishing company in Philadelphia, Pennsylvania, in 1879.
Approved Drug Products with Therapeutic Equivalence Evaluations, commonly known as the Orange Book, is a publication produced by the United States Food and Drug Administration (FDA), as required by the Drug Price and Competition Act (Hatch-Waxman Act). The Hatch-Waxman Act was created to '"strike a balance between two competing policy interests:
Taber's Cyclopedic Medical Dictionary is an encyclopedic medical dictionary published by F.A. Davis Company since 1940 by Clarence Wilbur Taber. [1] Taber's is a recommended medical reference book for libraries and attorneys. [2] [3] It is available in print, online, and in multiple mobile device formats. [4]
These effects are known from the drug's components as well as from other antibiotics. A very rare but dangerous reaction is Stevens–Johnson syndrome , a life-threatening condition affecting the skin, which has also been described under metronidazole and tetracycline as separate drugs.
The mechanisms of antiprotozoal drugs differ significantly drug to drug. For example, it appears that eflornithine , a drug used to treat trypanosomiasis , inhibits ornithine decarboxylase , while the aminoglycoside antibiotic/antiprotozoals used to treat leishmaniasis are thought to inhibit protein synthesis.