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Azithromycin, sold under the brand names Zithromax (in oral form) and Azasite (as an eye drop), is an antibiotic medication used for the treatment of several bacterial infections. [10] This includes middle ear infections , strep throat , pneumonia , traveler's diarrhea , and certain other intestinal infections . [ 10 ]
Azithromycin: Zithromax, Sumamed, Xithrone: Streptococcal infections, syphilis, upper respiratory tract infections, lower respiratory tract infections, mycoplasmal infections, Lyme disease: Nausea, vomiting, and diarrhea (especially at higher doses) Prolonged cardiac QT interval (especially erythromycin) Hearing loss (especially at higher doses ...
The first-line treatment for uncomplicated syphilis (primary or secondary stages) remains a single dose of intramuscular benzathine benzylpenicillin. [68] The bacterium is highly vulnerable to penicillin when treated early, and a treated individual is typically rendered non-infective in about 24 hours. [ 69 ]
In the 2010s, a single oral dose of azithromycin was shown to be as effective as intramuscular penicillin. [19] [12] Unlike penicillin, there is strong evidence that yaws is evolving antibiotic resistance to azithromycin; there are two known mutations in the bacterium, each of which can cause resistance and make the treatment ineffective. This ...
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The CDC recommendation is either a single oral dose (1 gram) of azithromycin, a single IM dose (250 mg) of ceftriaxone, oral (500 mg) of erythromycin three times a day for seven days, or oral (500 mg) of ciprofloxacin twice a day for three days. No Varicella zoster virus (VZV) Chickenpox
Laboratoires Delbert said it was coordinating with the health regulator to bring extencilline into the United States to address syphilis drug shortages, according to a letter on the FDA's website.
A noted drug interaction involves erythromycin and simvastatin, resulting in increased simvastatin levels and the potential for rhabdomyolysis. Another group of CYP3A4 substrates are drugs used for migraine such as ergotamine and dihydroergotamine ; their adverse effects may be more pronounced if erythromycin is associated.