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MADAM-6, or 2, N-dimethyl-4,5-methylenedioxyamphetamine, is a lesser-known recreational drug of the methamphetamine class, similar in structure to MDMA (ecstasy). [1] MADAM-6 was first synthesized by Alexander Shulgin. [2] In Shulgin's book PiHKAL, the minimum dosage is listed as greater than 280 mg, and the duration is unknown. [2]
5-10% of the drug (active substance); 80% of fillers, disintegrants, lubricants, glidants, and binders; and; 10% of compounds which ensure easy disintegration, disaggregation, and dissolution of the tablet in the stomach or the intestine. The dissolution time can be modified for a rapid effect or for sustained release.
Patrick Arnold (born 1966) [1] is an American organic chemist known for introducing androstenedione, 1-androstenediol, and methylhexanamine into the dietary supplement market, and for creating the designer steroid tetrahydrogestrinone, also known as THG and "the clear". [2]
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use.
A drug class is a group of medications and other compounds that share similar chemical structures, act through the same mechanism of action (i.e., binding to the same biological target), have similar modes of action, and/or are used to treat similar diseases. [1] [2] The FDA has long worked to classify and license new medications.
Piperidine is an organic compound with the molecular formula (CH 2) 5 NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH 2 –) and one amine bridge (–NH–). It is a colorless liquid with an odor described as objectionable, typical of amines. [6]
Dioscorides’ Materia Medica, c. 1334 copy in Arabic, describes medicinal features of various plants.. Pharmacognosy is the study of crude drugs obtained from medicinal plants, animals, fungi, and other natural sources. [1]
Adamantane is an organic compound with formula C 10 H 16 or, more descriptively, (CH) 4 (CH 2) 6. Adamantane molecules can be described as the fusion of three cyclohexane rings. The molecule is both rigid and virtually stress-free. Adamantane is the most stable isomer of C 10 H 16.