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The work-up for diagnosis is complex and the condition can be over-diagnosed. [1] [2] [better source needed] People diagnosed with warm autoimmune hemolytic anemia (WAIHA) caused by immunoglobulin G (IgG) [3] may also have a high number of immunoglobulin M antibodies. These antibodies are active at room temperature, but are believed to be ...
Traumatic hemolytic anemia [2]. Impact [2]; Macrovascular defects-prostheses [2]; Microvascular causes [2]. Disseminated intravascular hemolysis [2]; Thrombotic thrombocytopenic purpura [2]
Diagnosis is made by first ruling out other causes of hemolytic anemia, such as G6PD, thalassemia, sickle-cell disease. Clinical history is also important to elucidate any underlying illness or medications that may have led to the disease. [citation needed] Laboratory investigations are carried out to determine the etiology of the disease.
A positive direct antiglobulin test differentiates immune-mediated hemolytic anemia from a nonimmune-mediated cause. Other situations such as liver disease, post-transfusion or immunoglobulin administration, renal disease, and malignancy can cause a positive direct antiglobulin test. [1]
Cold agglutinins develop in more than 60% of patients with infectious mononucleosis, but hemolytic anemia is rare. Classic chronic cold agglutinin disease is idiopathic, associated with symptoms and signs in relation to cold exposure.
Each sample is incubated against a wide range of RBCs that together exhibit a full range of surface antigens (i.e. blood types). Cross matching; The indirect Coombs test is used to test a sample of the recipient's serum for antibodies against a sample of the blood donor's RBCs. This is sometimes called cross-matching blood.
Deployment Image Service and Management Tool (DISM) is a tool introduced in Windows 7 [10] and Windows Server 2008 R2 [10] that can perform servicing tasks on a Windows installation image, be it an online image (i.e. the one the user is running) or an offline image within a folder or WIM file. Its features include mounting and unmounting images ...
ISO images can be created from optical discs by disk imaging software, or from a collection of files by optical disc authoring software, or from a different disk image file by means of conversion. Software distributed on bootable discs is often available for download in ISO image format; like any other ISO image, it may be written to an optical ...