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Terbinafine is an antifungal medication used to treat pityriasis versicolor, fungal nail infections, and ringworm including jock itch and athlete's foot. [1] [2] [3] It is either taken by mouth or applied to the skin as a cream or ointment. [1] [4]
Clobetasol propionate is a corticosteroid that is used to treat skin conditions such as eczema, contact dermatitis, seborrheic dermatitis, steroid responsive dermatosis, and psoriasis (including scalp and plaque-type). [8] [9] It is applied to the skin as a cream, foam, gel, liquid, solution, ointment, or shampoo.
Tolnaftate , [1] sold under the brand name TAGRID, among others, is a synthetic thiocarbamate used as an anti-fungal agent that may be sold without medical prescription in most jurisdictions. It is supplied as a cream, powder, spray, liquid, and liquid aerosol . [ 2 ]
Whitfield's ointment is not advised for areas of thinner skin, such as the scrotum or the groin, and in such sites should only be used diluted to half-strength. [ 5 ] A systematic review of the medical literature comparing treatments for ringworm and jock itch was generally critical of the quality of data available.
Miconazole, sold under the brand name Monistat among others, is an antifungal medication used to treat ring worm, pityriasis versicolor, and yeast infections of the skin or vagina. [2] It is used for ring worm of the body, groin (jock itch), and feet (athlete's foot). [2] It is applied to the skin or vagina as a cream or ointment. [2] [3]
Antifungal resistance is a One Health concern, driven by multiple extrinsic factors, including extensive fungicidal use, overuse of clinical antifungals, environmental change and host factors. [1] Like resistance to antibacterials, antifungal resistance can be driven by antifungal use in agriculture.
Like the allylamine antifungals (e.g terbinafine), butenafine works by inhibiting the synthesis of ergosterol by binding to and inhibiting squalene epoxidase, an enzyme in the pathway used for creation of the sterols needed in fungal cell membranes. Lacking ergosterol, the cell membranes increase in permeability, allowing their contents to leak ...
Potassium permanganate is used as a medication for a number of skin conditions. [2] This includes fungal infections of the foot, impetigo, pemphigus, superficial wounds, dermatitis, and tropical ulcers. [3] [2] For tropical ulcers it is used together with procaine benzylpenicillin. [2] [3] It can be applied as a soaked dressing or a bath. [2]