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  2. Paracetamol poisoning - Wikipedia

    en.wikipedia.org/wiki/Paracetamol_poisoning

    Paracetamol poisoning, also known as acetaminophen poisoning, is caused by excessive use of the medication paracetamol (acetaminophen). [2] Most people have few or non-specific symptoms in the first 24 hours following overdose. These symptoms include feeling tired, abdominal pain, or nausea.

  3. Rumack–Matthew nomogram - Wikipedia

    en.wikipedia.org/wiki/Rumack–Matthew_nomogram

    The Rumack–Matthew nomogram, also known as the acetaminophen nomogram, is an acetaminophen toxicity nomogram. It plots serum concentration of acetaminophen against the time since ingestion, in order to predict possible liver toxicity and allow a clinician to decide whether to proceed with N-Acetylcysteine (NAC) treatment.

  4. Paracetamol - Wikipedia

    en.wikipedia.org/wiki/Paracetamol

    Within these estimates, unintentional acetaminophen overdose accounted for nearly 25 % of the emergency department visits, 10 % of the hospitalizations, and 25 % of the deaths." [110] [needs update] Overdoses are frequently related to high-dose recreational use of prescription opioids, as these opioids are most often combined with paracetamol ...

  5. Pharmacotoxicology - Wikipedia

    en.wikipedia.org/wiki/Pharmacotoxicology

    Acetaminophen (APAP) is a very common drug used to treat pain. High doses of acetaminophen has been shown to produce severe hepatotoxicity after being biotransformed to produce reactive intermediates. Acetaminophen is metabolized by CYP2E1 to produce NAPQI, which then causes significant oxidative stress due to increased reactive oxygen species ...

  6. NAPQI - Wikipedia

    en.wikipedia.org/wiki/NAPQI

    NAPQI, also known as NAPBQI or N-acetyl-p-benzoquinone imine, is a toxic byproduct produced during the xenobiotic metabolism of the analgesic paracetamol (acetaminophen). [1] It is normally produced only in small amounts, and then almost immediately detoxified in the liver.

  7. Is Roblox safe for kids? Here's what parents need to know. - AOL

    www.aol.com/lifestyle/roblox-safe-kids-heres...

    What age is Roblox for? Common Sense Media rates Roblox as most appropriate for ages 13+. “At that age kids have a bit more awareness about how to discern keeping themselves safe on platforms ...

  8. Tylenol (brand) - Wikipedia

    en.wikipedia.org/wiki/Tylenol_(brand)

    The active ingredient of its original flagship product is paracetamol (known in the United States, Canada, and various other countries as acetaminophen), an analgesic and antipyretic. Like the words paracetamol and acetaminophen, the brand name Tylenol is derived from a chemical name for the compound, N-acetyl-para-aminophenol (APAP). [1]

  9. Hydrocodone/paracetamol - Wikipedia

    en.wikipedia.org/wiki/Hydrocodone/paracetamol

    Each year, paracetamol overdose is linked to about 400 deaths and 42,000 hospitalizations. [22] In January 2011, the FDA asked manufacturers of prescription combination products that contain paracetamol to limit the amount of paracetamol to no more than 325 mg in each tablet or capsule within three years.