Search results
Results from the WOW.Com Content Network
Ramipril, sold under the brand name Altace among others, is an ACE inhibitor type medication used to treat high blood pressure, ... with or without proteinuria. [12]
Some believe ramipril's additional benefits may be shared by some or all drugs in the ACE-inhibitor class. However, ramipril currently remains the only ACE inhibitor for which such effects are actually evidence-based. [64] A meta-analysis confirmed that ACE inhibitors are effective and certainly the first-line choice in hypertension treatment.
The ratio of Cmax, AUC0-t and AUC0-∞ for Polycap and reference drugs was within 80-125% for atenolol, hydrochlorothiazide, ramipril, ramiprilat and dose normalized salicylic acid. However, for simvastatin the point estimate of Cmax, AUC0-t and AUC0-∞ for Ln-transformed data were significantly lower (~25%) and for its active metabolite ...
Losartan, the first ARB. Angiotensin II receptor blockers (ARBs), formally angiotensin II receptor type 1 (AT 1) antagonists, [1] also known as angiotensin receptor blockers, [2] [3] angiotensin II receptor antagonists, or AT 1 receptor antagonists, are a group of pharmaceuticals that bind to and inhibit the angiotensin II receptor type 1 (AT 1) and thereby block the arteriolar contraction and ...
[1] [16] Lisinopril absorption is not affected by the presence of food in the gastrointestinal tract. [18] [20] [21] Studies in rats indicate that lisinopril crosses the blood-brain barrier poorly. Multiple doses of lisinopril in rats result in little or no accumulation in brain tissue. [22]
S-8307 and S-8308 have moderate potency, short duration of action and limited oral bioavailability, however they are selective and competitive AT 1 receptor antagonists without partial agonist activity. [1] A group at DuPont postulated that both Ang II and the Takeda leads were bound at the same receptor site. [7]
An ACE inhibitor and thiazide combination is a drug combination used to treat hypertension (high blood pressure). They are given by mouth.ACE inhibitors reduce the activity of angiotensin-converting enzyme (ACE) which produces angiotensin II, a hormone that constricts blood vessels.
This drug article relating to the cardiovascular system is a stub. You can help Wikipedia by expanding it.