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  2. XY sex-determination system - Wikipedia

    en.wikipedia.org/wiki/XY_sex-determination_system

    Offspring have two sex chromosomes: an offspring with two X chromosomes (XX) will develop female characteristics, and an offspring with an X and a Y chromosome (XY) will develop male characteristics, except in various exceptions such as individuals with Swyer syndrome, that have XY chromosomes and a female phenotype, and de la Chapelle Syndrome ...

  3. Sexual differentiation in humans - Wikipedia

    en.wikipedia.org/wiki/Sexual_differentiation_in...

    In the absence of a Y chromosome, the fetus will undergo female development. This is because of the presence of the sex-determining region of the Y chromosome, also known as the SRY gene. [5] Thus, male mammals typically have an X and a Y chromosome (XY), while female mammals typically have two X chromosomes (XX).

  4. Sex-determination system - Wikipedia

    en.wikipedia.org/wiki/Sex-determination_system

    The human Y-chromosome has had about 5 strata since the origin of the X and Y chromosomes about 300 Mya from a pair of autosomes. Each stratum was formed when a pseudoautosomal region (PAR) of the Y chromosome is inverted, stopping it from recombination with the X chromosome. Over time, each inverted region decays, possibly due to Muller's ratchet.

  5. Sex differences in human physiology - Wikipedia

    en.wikipedia.org/wiki/Sex_differences_in_human...

    The X-chromosome carries a larger number of genes in comparison to the Y-chromosome. In humans, X-chromosome inactivation enables males and females to have an equal expression of the genes on the X-chromosome since females have two X-chromosomes while males have a single X and a Y chromosome. X-chromosome inactivation is random in the somatic ...

  6. Weighted least squares - Wikipedia

    en.wikipedia.org/wiki/Weighted_least_squares

    Weighted least squares (WLS), also known as weighted linear regression, [1] [2] is a generalization of ordinary least squares and linear regression in which knowledge of the unequal variance of observations (heteroscedasticity) is incorporated into the regression.

  7. Pseudoautosomal region - Wikipedia

    en.wikipedia.org/wiki/Pseudoautosomal_region

    Normal females also possess two copies of pseudoautosomal genes, as each of their two X chromosomes contains a pseudoautosomal region. Crossing over between the X and Y chromosomes is normally restricted to the pseudoautosomal regions; thus, pseudoautosomal genes exhibit an autosomal, rather than sex-linked, pattern of inheritance. So, females ...

  8. What to know about JD Vance’s 'Mamaw,' Bonnie Blanton ... - AOL

    www.aol.com/news/know-jd-vance-mamaw-bonnie...

    Mamaw was a Democrat . Though JD Vance makes up one-half of the Republican ticket for the 2024 election, his beloved Mamaw was a staunch Democrat, as was her husband, James Vance, aka “Papaw.” ...

  9. Y chromosome - Wikipedia

    en.wikipedia.org/wiki/Y_chromosome

    The Y chromosome is one of two sex chromosomes in therian mammals and other organisms.Along with the X chromosome, it is part of the XY sex-determination system, in which the Y is the sex-determining chromosome because the presence of the Y chromosome causes offspring produced in sexual reproduction to be of male sex.