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Nevus lipomatosus superficialis (NLS or NLCS, also known as nevus lipomatosis of Hoffman and Zurhelle [1]) is characterized by soft, yellowish papules or cerebriform plaques, usually of the buttock or thigh, less often of the ear or scalp, with a wrinkled rather than warty surface.
[1] [3] Diagnosis is typically based on a physical exam. [1] Occasionally medical imaging or tissue biopsy is used to confirm the diagnosis. [1] Treatment is typically by observation or surgical removal. [1] Rarely, the condition may recur following removal, but this can generally be managed with repeat surgery. [1]
Both tests are useful to establish the diagnosis of multiple symmetric lipomatosis, although magnetic resonance imaging provides more details and may be used when lipomas are large, deep, or have infiltrated muscle fibers or nerves. In some cases, a biopsy of the lipomas may be necessary to confirm the diagnosis. [3]
Angiolipoma is a subcutaneous nodule with vascular structure, having all other features of a typical lipoma. They are commonly painful. [1]: 624 [2] Angiolipomas manifest as multiple painful subcutaneous nodules commonly on the upper limbs. The can occur sporadically, with a family history or after trauma.
Chondroid lipoma is an uncommon soft tissue fatty tumor that can develop in deeper or superficial tissues. It often manifests as a painless mass. [3] The subcutis, superficial muscular fascia, or skeletal muscles of the limbs and limb girdles, trunk, head, and neck are where the majority of lesions are located. [4]
Mediastinal lipomatosis. Lipomatosis is believed to be an autosomal dominant condition in which multiple lipomas are present on the body. Many discrete, encapsulated lipomas form on the trunk and extremities, with relatively few on the head and shoulders. [1]
Dercum's disease is a rare condition characterized by multiple painful fatty tumors, called lipomas, that can grow anywhere in subcutaneous fat across the body. [1] Sometimes referred as adiposis dolorosa in medical literature, Dercum’s disease is more of a syndrome than a disease (because it has several clinically recognizable features, signs, and symptoms that are characteristic of it and ...
Most cases of pleomorphic lipoma are seen in the subcutaneous tissue of the back, shoulder, and posterior neck. [2] Less commonly, it can also happen in odd places like the tongue, [3] vulva, [4] palm, [5] tonsillar fossa, [6] orbit, [7] and oral cavity. [8] The lesion usually presents as a subcutaneous lump that is circumscribed, like the ...