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Nail fungus can be painful and cause permanent damage to nails. It may lead to other serious infections if the immune system is suppressed due to medication, diabetes or other conditions. The risk is most serious for people with diabetes and with immune systems weakened by leukemia or AIDS, or medication after organ transplant.
Trichophyton rubrum is a dermatophytic fungus in the phylum Ascomycota.It is an exclusively clonal, [2] anthropophilic saprotroph that colonizes the upper layers of dead skin, and is the most common cause of athlete's foot, fungal infection of nail, jock itch, and ringworm worldwide. [3]
The ring shape of dermatophyte lesions result from outward growth of the fungi. [3] The fungi spread in a centrifugal pattern in the stratum corneum, which is the outermost keratinized layer of the skin. [3] For nail infections, the growth initiates through the lateral or superficial nail plates, then continues throughout the nail. [3]
The Latin names are for the conditions (disease patterns), not the agents that cause them. The disease patterns below identify the type of fungus that causes them only in the cases listed: Dermatophytosis Tinea pedis (athlete's foot): fungal infection of the feet; Tinea unguium: fungal infection of the fingernails and toenails, and the nail bed
Trichophyton is a genus of fungi, which includes the parasitic varieties that cause tinea, including athlete's foot, ringworm, jock itch, and similar infections of the nail, beard, skin and scalp. Trichophyton fungi are molds characterized by the development of both smooth-walled macro- and microconidia.
Athlete's foot fungus may infect any part of the foot, but most often grows between the toes. [3] The next most common area is the bottom of the foot. [6] The same fungus may also affect the nails or the hands. [4] It is a member of the group of diseases known as tinea. [7]
Epidermophyton floccosum is a filamentous fungus that causes skin and nail infections in humans. [1] This anthropophilic dermatophyte can lead to diseases such as tinea pedis (athlete's foot), tinea cruris, tinea corporis and onychomycosis.
The nail is an unguis, meaning a keratin structure at the end of a digit. Other examples of ungues include the claw, hoof, and talon. The nails of primates and the hooves of running mammals evolved from the claws of earlier animals. [38] In contrast to nails, claws are typically curved ventrally (downwards in animals) and compressed sideways.