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Galactose-α-1,3-galactose, commonly known as alpha gal and the Galili antigen, is a carbohydrate found in most mammalian cell membranes. It is not found in catarrhines , [ 1 ] including humans, who have lost the glycoprotein alpha-1,3-galactosyltransferase ( GGTA1 ) gene.
α-Galactosidase ( EC 3.2.1.22, α-GAL, α-GAL A; systematic name α-D-galactoside galactohydrolase) is a glycoside hydrolase enzyme that catalyses the following reaction: [1] Hydrolysis of terminal, non-reducing α- D -galactose residues in α- D -galactosides, including galactose oligosaccharides, galactomannans and galactolipids
This galactose molecule is called the H antigen. [28] [29] [30] Blood type A, B, AB, and O differ only in the sugar (red molecule in the illustration) linked with the penultimate galactose. For blood type B, this linked sugar is an α-1‐3‐linked galactose. Using α-GAL, this terminal galactose molecule can be removed, converting RBC to type O.
Soyasapogenol B glucuronide galactosyltransferase (EC 2.4.1.272, UDP-galactose:SBMG-galactosyltransferase, UGT73P2, GmSGT2 (gene), UDP-galactose:soyasapogenol B 3-O-glucuronide beta-D-galactosyltransferase) is an enzyme with systematic name UDP-alpha-D-galactose:soyasapogenol B 3-O-glucuronide beta-D-galactosyltransferase. [1]
Uridine diphosphate galactose (UDP-galactose) is an intermediate in the production of polysaccharides. [1] It is important in nucleotide sugars metabolism , and is the substrate for the transferase B4GALT5 .
Alpha-gal syndrome (AGS), also known as alpha-gal allergy or mammalian meat allergy (MMA), [1] is a type of acquired allergy characterized by a delayed onset of symptoms (3–8 hours) after ingesting mammalian meat. The condition results from past exposure to certain tick bites and was first reported in 2002.
Galactokinase is an enzyme (phosphotransferase) that facilitates the phosphorylation of α-D-galactose to galactose 1-phosphate at the expense of one molecule of ATP. [1] Galactokinase catalyzes the second step of the Leloir pathway, a metabolic pathway found in most organisms for the catabolism of α-D-galactose to glucose 1-phosphate. [2]
"50 YouTubers Fight for $1,000,000" is a YouTube video by American YouTuber Jimmy Donaldson, known on the platform as MrBeast. The video, described by Donaldson as his "biggest video ever," featured fifty YouTubers from around the world competing to stay inside a large glass cube for as long as possible while completing challenges. [1]