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Gastrin is a linear peptide hormone produced by G cells of the duodenum and in the pyloric antrum of the stomach.It is secreted into the bloodstream. The encoded polypeptide is preprogastrin, which is cleaved by enzymes in posttranslational modification to produce progastrin (an intermediate, inactive precursor) and then gastrin in various forms, primarily the following three:
Gastritis is the inflammation of the lining of the stomach. [1] It may occur as a short episode or may be of a long duration. [1] There may be no symptoms but, when symptoms are present, the most common is upper abdominal pain (see dyspepsia). [1]
Zollinger–Ellison syndrome (Z-E syndrome) is a rare disease in which tumors cause the stomach to produce too much acid, resulting in peptic ulcers. Symptoms include abdominal pain and diarrhea. The syndrome is caused by the formation of a gastrinoma, a neuroendocrine tumor that secretes a hormone called gastrin. [2]
Abdominal pain, also known as a stomach ache, is a symptom associated with both non-serious and serious medical issues. Since the abdomen contains most of the body's vital organs, it can be an indicator of a wide variety of diseases.
The main function of gastrin is to regulate acid secretion. [2] During digestion, only gastrin is released into the bloodstream and stimulates the secretion of hydrochloric acid in the stomach as well as pancreatic digestive enzymes. In humans, progastrin is encoded by the GAST [3] gene. Progastrin is expressed primarily in stomach tissue.
Woman with stomach pain. (Getty Images) ... but temporary upset stomach symptoms appear much faster — within a couple of hours," Dr. Alhassani adds. "However, symptoms from an upset stomach will ...
If in addition to a stomach ache, you're experiencing other symptoms of constipation, such as bloating or gas, add more fiber to your diet. Fill your plate with more fruits and vegetables, whole ...
A condition that is a result of stomach contents consistently coming back up into the esophagus causing troublesome symptoms or complications. [19] Symptoms are considered troublesome based on how disruptive they are to a patient's daily life and well-being. This definition was standardized by the Montreal Consensus in 2006. [20]