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  2. Factor VIII (medication) - Wikipedia

    en.wikipedia.org/wiki/Factor_VIII_(medication)

    A purified factor VIII concentrate is made from human blood plasma. [14] A recombinant version is also available. [13] People may develop antibodies to factor VIII such that this medication becomes less effective. [15] Factor VIII was first identified in the 1940s and became available as a medication in the 1960s.

  3. Efanesoctocog alfa - Wikipedia

    en.wikipedia.org/wiki/Efanesoctocog_alfa

    Efanesoctocog alfa is a recombinant DNA-derived, Factor VIII concentrate indicated for use in adults and children with hemophilia A (congenital factor VIII deficiency) for routine prophylaxis to reduce the frequency of bleeding episodes; on-demand treatment & control of bleeding episodes; and perioperative management of bleeding.

  4. Efmoroctocog alfa - Wikipedia

    en.wikipedia.org/wiki/Efmoroctocog_alfa

    Efmoroctocog alfa, sold under the brand name Elocta among others, is a medication for the treatment and prophylaxis of bleeding in people with hemophilia A. [5] [6] [7] Efmoroctocog alfa is a recombinant human coagulation factor VIII, Fc fusion protein (rFVIIIFc). [5]

  5. Damoctocog alfa pegol - Wikipedia

    en.wikipedia.org/wiki/Damoctocog_alfa_pegol

    Damoctocog alfa pegol, sold under the brand name Jivi is a recombinant DNA-derived, Factor VIII concentrate used to treat hemophilia A. [5] [6] The most common side effects include headache, cough, nausea, and fever. [5] Damoctocog alfa pegol was approved for medical use in the United States in August 2018, [7] and in the European Union in ...

  6. Susoctocog alfa - Wikipedia

    en.wikipedia.org/wiki/Susoctocog_alfa

    Susoctocog alfa, sold under the brand name Obizur, is a medication used for the treatment of bleeding episodes in adults with acquired haemophilia, a bleeding disorder caused by the spontaneous development of antibodies that inactivate factor VIII.

  7. Moroctocog alfa - Wikipedia

    en.wikipedia.org/wiki/Moroctocog_alfa

    It replaces the missing factor VIII, thereby helping the blood to clot and giving temporary control of bleeding. [6] The human coagulation factor VIII in moroctocog alfa is not extracted from human blood but is produced by a method known as 'recombinant DNA technology': it is made by a cell that has received a gene (DNA), which makes it able to ...

  8. Turoctocog alfa - Wikipedia

    en.wikipedia.org/wiki/Turoctocog_alfa

    Turoctocog alfa (trade name NovoEight) is a recombinant antihemophilic factor VIII used for the treatment of and prophylaxis of bleeding patients with haemophilia A. It is marketed by Novo Nordisk. [7] [9] [13] It was approved in the United States, the European Union, and Japan in 2013. [14] [15] [11] [9]

  9. Factor VIII - Wikipedia

    en.wikipedia.org/wiki/Factor_VIII

    Factor VIII was first characterized in 1984 by scientists at Genentech. [13] The gene for factor VIII is located on the X chromosome (Xq28). The gene for factor VIII presents an interesting primary structure, as another gene is embedded in one of its introns. [14]

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