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Biotin has no effect on thyroid hormone levels or thyroid function in the body. However, biotin can interfere with the measurement of hormone levels in the laboratory, making them inaccurate. This is because biotin is added as a reagent during some of the laboratory methods.
Negative side effects of biotin. Biotin is typically considered to be a safe supplement. It’s water-soluble, ... Thyroid disease. Heart disease. Pregnancy. Anemia. Cancer.
Most commonly, biotin use can result in falsely high levels of T 4 and T 3 and falsely low levels of TSH, leading to either a wrong diagnosis of hyperthyroidism or that the thyroid hormone dose is too high.
Biotin negatively impacts thyroid lab tests and may cause falsely elevated numbers. Biotin does NOT, however, directly alter your thyroid function so even though your numbers may be high your symptoms will not match your lab tests. DOWNLOAD FREE RESOURCES. Foods to Avoid if you Have Thyroid Problems:
High amounts of biotin can create false positives in laboratory tests for thyroid disease. Takeaway Your body makes enough biotin on its own through your dietary intake each day.
28 Comments. It’s alarming to get a laboratory test result that shows a serious problem. Learning later that the test might have given a false reading is also frustrating. One reader discovered that you should beware of biotin if you are having thyroid tests run. Why Should You Beware of Biotin? Q.
People taking biotin supplements may have falsely low thyroid stimulating hormone (TSH), and falsely high levels of triiodothyronine (T3) or thyroxine (T4). This can lead to an incorrect diagnosis of hyperthyroidism (overactive thyroid).
At high doses (10,000 times RDI), biotin improves clinical outcomes and quality of life in patients with progressive multiple sclerosis (MS). It has been reported to cause interference in immunoassays resulting in abnormal thyroid function tests.
In contrast, at Greenlee’s lab, biotin can lead to falsely low TSH results, but free T3 and free T4 tests are not affected. Biotin can also cause her lab’s assay for thyrotropin receptor antibodies (TRAb) to be falsely positive, which could lead to a misdiagnosis of Graves disease.
After repeating the thyroid function tests in our laboratory, we believed that the main culprit was the 20 mg biotin that caused such interference with the thyroid bioassay (pseudohyperthyroidism). We advised ZR to discontinue biotin and to repeat the test after 24 hours.