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The snoRNAs guide covalent modifications of rRNA, tRNA and snRNAs; RNase MRP cleaves the internal transcribed spacer 1 between 18S and 5.8S rRNAs. The ubiquitous ncRNA, RNase P, is an evolutionary relative of RNase MRP. [31] RNase P matures tRNA sequences by generating mature 5'-ends of tRNAs through cleaving the 5'-leader elements of precursor ...
A Medical logic Module is composed of four categories, namely maintenance, library, knowledge and resources, with appropriate slots. [2] Arden Syntax is an instance of a Knowledge Resource-Centric Knowledge Integration Architecture, where the knowledge resources command the delivery mechanisms of clinical decision support system.
Core residues are often conserved in a protein family, whereas the residues in loops are less conserved, unless they are involved in the protein's function. Protein tertiary structure can be divided into four main classes based on the secondary structural content of the domain. [25] All-α domains have a domain core built exclusively from α ...