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Diagnosis is based on clinical and laboratory findings of low serum osmolality and low serum sodium. [13] Urinalysis reveals a highly concentrated urine with a high fractional excretion of sodium (high sodium urine content compared to the serum sodium). [14] A suspected diagnosis is based on a serum sodium under 138.
Antipsychotics have been reported to cause hyponatremia in a review of medical articles from 1946 to 2016. [25] Available evidence suggests that all classes of psychotropics, i.e., antidepressants, antipsychotics, mood stabilizers, and sedative/hypnotics can lead to hyponatremia. Age is a significant factor for drug induced hyponatremia. [26]
These electrolytes must be replaced to keep the electrolyte concentrations of the body fluids constant. Hyponatremia, or low sodium, is the most commonly seen type of electrolyte imbalance. [12] [13] Treatment of electrolyte imbalance depends on the specific electrolyte involved and whether the levels are too high or too low. [3]
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Hypoosmolar hyponatremia is a condition where hyponatremia is associated with a low plasma osmolality. [1] The term "hypotonic hyponatremia" is also sometimes used.[2]When the plasma osmolarity is low, the extracellular fluid volume status may be in one of three states: low volume, normal volume, or high volume.
Nature Reviews Nephrology is a monthly peer-reviewed review journal published by Nature Portfolio. It was established as Nature Clinical Practice Nephrology in 2005, but change name in 2009. [1] [2] [3] The editor-in-chief is Susan Allison. [4]
Journal of Dental Research and Review; Journal of Dental and Allied Sciences; Journal of Dermatology and Dermatologic Surgery; Journal of Diabetes and Endocrine Practice; Journal of Diabetology (not to be confused with Journal of Diabetology published by Allied Academies) Journal of Digestive Endoscopy; Journal of Dr. NTR University of Health ...