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Opium tincture is indicated for the treatment of severe fulminant (intense, prolific) diarrhea that does not respond to standard therapy (e.g., Imodium or Lomotil). [31] The usual starting dose is 0.3 mL to 0.6 mL (about six to 12 drops) in a glass of water or juice four times a day. [31]
Decreasing intestinal motility prolongs the transit time of food content through the digestive tract, which allows for more fluid absorption; thereby alleviating diarrhea symptoms and improving stool consistency and frequency. [4] Unlike other opiates, loperamide does not cross the blood brain barrier, so there is minimal risk for abuse. [5]
Kaopectate is an orally taken medication for the treatment of mild diarrhea. It is also sometimes used to treat indigestion, nausea, and stomach ulcers. The active ingredients have varied over time, and are different between the United States and Canada. The original active ingredients were kaolinite and pectin.
Loperamide, sold under the brand name Imodium, among others, [1] is a medication of the opioid receptor agonist class used to decrease the frequency of diarrhea. [ 5 ] [ 4 ] It is often used for this purpose in irritable bowel syndrome , inflammatory bowel disease , short bowel syndrome , [ 4 ] Crohn's disease , and ulcerative colitis . [ 5 ]
Racecadotril is used for the treatment of acute diarrhea in children and adults and has better tolerability than loperamide, as it causes less constipation and flatulence. [6] [7] Several guidelines have recommended racecadotril use in addition to oral rehydration treatment in children with acute diarrhea. [8]
Another absorbent agent used for the treatment of mild diarrhea is kaopectate. Racecadotril an antisecretory medication may be used to treat diarrhea in children and adults. [107] It has better tolerability than loperamide, as it causes less constipation and flatulence. [115] However, it has little benefit in improving acute diarrhea in ...
In 2002, a journal article suggested its use in treatment of H. pylori infections in children. [3] Furazolidone has also been used for giardiasis (due to Giardia lamblia), amoebiasis, and shigellosis, although it is not a first-line treatment. [4]
Alosetron, sold under the brand name Lotronex among others, is a 5-HT 3 antagonist used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in females only. It was patented in 1987 and approved for medical use in 2002. [2] It is currently marketed by Prometheus Laboratories Inc. .
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