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The increase in pulse pressure may result in increased damage to blood vessels in target organs such as the brain or kidneys. [23] [24] This effect may be exaggerated if the increase in arterial stiffness results in reduced wave reflection and more propagation of the pulsatile pressure into the microcirculation. [23]
A stroke is when part of your brain loses its blood supply. Strokes are a type of cerebrovascular disease affecting the blood vessels in your brain. The main types of stroke are:
Stroke is caused by marked narrowing or closure of arteries going to the brain; lack of adequate blood supply leads to the death of the cells of the affected tissue. [26] Peripheral arteries, which supply blood to the legs, arms, and pelvis, also experience marked narrowing due to plaque rupture and clots. Symptoms of the narrowing are pain and ...
Cerebral blood flow (CBF) is the blood supply to the brain in a given period of time. [8] In an adult, CBF is typically 750 millilitres per minute or 15.8 ± 5.7% of the cardiac output. [9] This equates to an average perfusion of 50 to 54 millilitres of blood per 100 grams of brain tissue per minute. [10] [11] [12]
In turn, the brain is more vulnerable to ischemic insults as there is a dysregulation in the supply of blood and oxygen. [19] More specifically, hypertension inflicts damage to small resistance arteries, which supply nutrients to the internal capsule, brainstem, thalamus, cerebellum, and basal ganglia, and cause cell death and tissue ...
Atrial fibrillation causes blood clots to form within the heart, which may travel to the arteries within the brain and cause an embolism. The embolism prevents blood flow to the brain, which leads to a stroke. [26] An aneurysm is an abnormal bulging of small sections of arteries, which increases the risk of artery rupture.
Infarction occurs as a result of prolonged ischemia, which is the insufficient supply of oxygen and nutrition to an area of tissue due to a disruption in blood supply. [5] The blood vessel supplying the affected area of tissue may be blocked due to an obstruction in the vessel (e.g., an arterial embolus, thrombus, or atherosclerotic plaque ...
For those with the rare health condition, which causes uncontrollable muscle spasms, daily life is challenging without help and treatment. A Look Into the Daily Life of Those Living with Stiff ...