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[8] [33] The pharmacokinetics of testosterone cypionate are said to be the same as those of testosterone enanthate, with "extremely comparable" patterns of testosterone release. [35] [33] Due to their varying and different elimination half-lives, the different intramuscular testosterone esters are administered with differing frequencies. [74]
[4] [3] As such, testosterone cypionate and testosterone enanthate are considered to be "functionally interchangeable" as medications. [4] For reference, testosterone enanthate has an elimination half-life of 4.5 days and a mean residence time of 8.5 days and requires frequent administration of approximately once per week. [21]
Testosterone undecanoate: Castor oil solution: Intramuscular injection: 11.4 days: 33.9 days: 36.0 days Testosterone buciclate a: Aqueous suspension: Intramuscular injection: 25.8 days: 29.5 days: 60.0 days Notes: Testosterone cypionate has similar pharmacokinetics to Testosterone enanthate. Footnotes: a = Never marketed. Sources: [1] [2] [3]
Testosterone enanthate has an elimination half-life of 4.5 days and a mean residence time of 8.5 days when used as a depot intramuscular injection. [2] It requires frequent administration of approximately once per week, and large fluctuations in testosterone levels result with it, with levels initially being elevated and supraphysiological. [2]
Mixed testosterone esters b: Oil solution: Testosid Depot: 14–20 days Testosterone enanthate: Oil solution: Delatestryl: 14–28 days Testosterone cypionate: Oil solution: Depovirin: 14–28 days Mixed testosterone esters c: Oil solution: Sustanon 250: 28 days Testosterone undecanoate: Oil solution: Aveed, Nebido: 100 days Testosterone ...
Testosterone cypionate and testosterone enanthate were formerly available in combination with estradiol cypionate and estradiol valerate, respectively, under the brand names Depo-Testadiol and Ditate-DS, respectively, as oil solutions for intramuscular injection, but these formulations have been discontinued. [57]
Testosterone undecanoate has a very long elimination half-life and mean residence time when given as a depot intramuscular injection. [27] [7] [8] Its elimination half-life is 20.9 days and its mean residence time is 34.9 days in tea seed oil, while its elimination half-life is 33.9 days and its mean residence time is 36.0 days in castor oil.
Testosterone enanthate: Delatestryl: Oil solution: 50–250 mg 1x/1–4 weeks Xyosted: Auto-injector: 50–100 mg 1×/week Testosterone cypionate: Depo-Testosterone: Oil solution: 50–250 mg 1x/1–4 weeks Testosterone isobutyrate: Agovirin Depot: Aqueous suspension: 50–100 mg 1x/1–2 weeks Testosterone phenylacetate b: Perandren, Androject ...
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