Search results
Results from the WOW.Com Content Network
Trifluoroacetic anhydride was originally prepared by the dehydration of trifluoroacetic acid with phosphorus pentoxide. [2] The dehydration might also be carried out with excess α-halogenated acid chlorides. For example, with dichloroacetyl chloride: [3] 2 CF 3 COOH + Cl 2 CHCOCl → (CF 3 CO) 2 O + Cl 2 CHCOOH + HCl
Trifluoroacetic acid in a beaker. TFA is the precursor to many other fluorinated compounds such as trifluoroacetic anhydride, trifluoroperacetic acid, and 2,2,2-trifluoroethanol. [4] It is a reagent used in organic synthesis because of a combination of convenient properties: volatility, solubility in organic solvents, and its strength as an ...
Alkenes can be made from alcohols by dehydration. This conversion, among others, is used in converting biomass to liquid fuels. [2] The conversion of ethanol to ethylene is a fundamental example: [3] [4] CH 3 CH 2 OH → H 2 C=CH 2 + H 2 O. The reaction is accelerated by acid catalysts such as sulfuric acid and certain zeolites.
Trifluoroacetic acid is a widely employed acid, used for example in the synthesis of peptides.Its esters are useful in analytical chemistry. Longer-chain perfluoroalkyl carboxylic acids, e.g. with five to nine carbons, are useful fluorosurfactants and emulsifiers used in the production of polytetrafluoroethylene (Teflon) and related fluoropolymers.
When using oxalyl chloride as the dehydration agent, the reaction must be kept colder than −60 °C to avoid side reactions. With cyanuric chloride [11] or trifluoroacetic anhydride [12] instead of oxalyl chloride, the reaction can be warmed to −30 °C without side reactions.
Reductions with hydrosilanes are methods used for hydrogenation and hydrogenolysis of organic compounds.The approach is a subset of ionic hydrogenation.In this particular method, the substrate is treated with a hydrosilane and auxiliary reagent, often a strong acid, resulting in formal transfer of hydride from silicon to carbon. [1]
Cleaved with trifluoroacetic acid in water/tetrahydrofuran, [9] acetic acid in water/tetrahydrofuran, ... they are formed as a rule from glycols through dehydration.
Copper trifluoroacetate can be obtained by reacting trifluoroacetic acid with copper oxide, copper hydroxide or basic copper carbonate.Acetone can replace the water molecules in copper trifluoroacetate hydrate, and under reduced pressure conditions, the acetone can be removed to obtain anhydrous material.