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The side effects are associated with the dosage, type of drug used and the duration of treatment. Systemic corticosteroids are not considered first-line therapy for chronic management due to common and significant risks of adverse reactions .
Antiserum or drug treatment should be stopped as soon as possible. [2] [3] Once treatment has stopped, symptoms usually resolve within seven days. [3] Outcomes are generally good. [4] Corticosteroids, antihistamines, and analgesics are the main line of treatment. [3] The choice depends on the severity of the reaction. Prednisone may be used in ...
Treatment to protect the airway may include intubation or cricothyroidotomy. [1] Histamine-related angioedema can be treated with antihistamines , corticosteroids , and epinephrine . [ 1 ] In those with bradykinin-related disease a C1 esterase inhibitor , ecallantide , or icatibant may be used. [ 1 ]
Drug-induced angioedema is a known complication of the use of angiotensin-converting enzyme (ACE) inhibitors, angiotensin II antagonists (ARBs), and Angiotensin-Neprilysin Inhibitor LCZ969. [ 1 ] : 120 The angioedema appears to be dose dependent as it may resolve with decreased dose.
Hypersensitivity reactions are idiosyncratic reactions to a drug. [1] Although the term NSAID was introduced to signal a comparatively low risk of adverse effects, [2] NSAIDs do evoke a broad range of hypersensitivity syndromes. These syndromes have recently been classified by the European Academy of Allergy and Clinical Immunology Task Force ...
Side effects experienced while taking cinnarizine range from the mild to the quite severe. Possible side effects include drug-induced parkinsonism, [22] drowsiness, sweating, dry mouth, headache, skin problems, lethargy, gastrointestinal irritation, hypersensitivity reactions, as well as movement problems, muscle rigidity, and tremor. [15]
The most common adverse effects noted for second-generation agents include drowsiness, fatigue, headache, nausea and dry mouth. [4] Continuous and/or cumulative use of anticholinergic medications, including first-generation antihistamines, is associated with higher risk for cognitive decline and dementia in older people. [8] [9]
The incidence of life-threatening hypersensitivity reactions occurring during surgery and anesthesia is around one in 10,000 procedures. [1] Severe allergic reactions to anesthetic medications are rare and are usually attributable to factors other than the anesthetic.