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The trophoblast (from Greek trephein: to feed; and blastos: germinator) is the outer layer of cells of the blastocyst. Trophoblasts are present four days after fertilization in humans. [ 1 ] They provide nutrients to the embryo and develop into a large part of the placenta .
They are sometimes called intermediate trophoblast. [1] EVTs that derive from CYT cells on the surface of placental chorionic villi that come into contact with the uterine wall - at the placental bed - begin to express the HLA-G antigen. [2] Extravillous trophoblast (EVT) cells migrate from anchoring villi, and invade into the decidua basalis.
Both are composed of intermediate trophoblast, but their morphological features and clinical presentation can differ significantly. Exaggerated placental site is a benign, non cancerous lesion with an increased number of implantation site intermediate trophoblastic cells that infiltrate the endometrium and the underlying myometrium. An ...
"Cytotrophoblast" is the name given to both the inner layer of the trophoblast (also called layer of Langhans) or the cells that live there.It is interior to the syncytiotrophoblast and external to the wall of the blastocyst in a developing embryo.
In the placenta, the intervillous space is the space between chorionic villi, and contains maternal blood.. The trophoblast, which is a collection of cells that invades the maternal endometrium to gain access to nutrition for the fetus, proliferates rapidly and forms a network of branching processes which cover the entire embryo and invade and destroy the maternal tissues.
Image showing trophoblast differentiated into the two layers of cytotrophoblast and syncytiotrophoblast during implantation. It is the outer layer of the trophoblasts and actively invades the uterine wall, during implantation, rupturing maternal capillaries and thus establishing an interface between maternal blood and embryonic extracellular fluid, facilitating passive exchange of material ...
It possesses an inner cell mass (ICM) also known as the embryoblast which subsequently forms the embryo, and an outer layer of trophoblast cells called the trophectoderm. [1] [2] This layer surrounds the inner cell mass and a fluid-filled cavity or lumen known as the blastocoel. [3] In the late blastocyst, the trophectoderm is known as the ...
Gestational trophoblastic neoplasia (GTN) is group of rare diseases related to pregnancy and included in gestational trophoblastic disease (GTD) in which abnormal trophoblast cells grow in the uterus. [1] GTN can be classified into benign and malignant lesions.