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Several chemicals have been shown to be effective in skin whitening, while some have proven to be toxic or have questionable safety profiles. This includes mercury compounds which may cause neurological problems and kidney problems. [1] In a number of African countries, between 25 and 80% of women regularly use skin whitening products. [2]
Tyrosinase is an enzyme needed in melanin synthesis in the melanin producing cell of the skin, the melanocyte. By reducing the activity of tyrosinase, β-arbutin reduces the synthesis of melanin, leading to a lighter skin tone and the diminished appearance of hyperpigmentation. It is not as potent an inhibitor of tyrosinase as α-arbutin. [6]
Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis . Melanin is a class of pigment responsible for producing color in the body in places such as the eyes, skin, and hair.
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[1] Most commonly, depigmentation of the skin is linked to people born with vitiligo, which produces differing areas of light and dark skin. Monobenzone also causes skin depigmentation. Increasingly, people who are not afflicted with vitiligo experiment with lower concentrations of monobenzone creams in the hope of lightening their skin tone ...
It is caused by melanocyte or melanin depletion, or a decrease in the amino acid tyrosine, which is used by melanocytes to make melanin. [2] Some common genetic causes include mutations in the tyrosinase gene or OCA2 gene. [3] [4] As melanin pigments tend to be in the skin, eye, and hair, these are the commonly affected areas in those with ...
Lotion and shampoo at the Banff Centre. Lotion is a low-viscosity topical preparation intended for application to the skin. By contrast, creams and gels have higher viscosity, typically due to lower water content. [1] [2] Lotions are applied to external skin with bare hands, a brush, a clean cloth, or cotton wool.
Indoor tanning lotions accelerate the tanning process, by promoting the production of melanin. [1] Increasing blood flow to the skin is a proposed mechanism, which may in turn stimulate production of melanin by melanocytes. [2] Historically, indoor tanning lotions have contained no sunscreen and offer no protection from the sun. However, many ...
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