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  2. CNS metastasis - Wikipedia

    en.wikipedia.org/wiki/CNS_metastasis

    Cancer cells spread by intravasation. CNS metastasis is the spread and proliferation of cancer cells from their original tumour to form secondary tumours in portions of the CNS. [1] Typically, this progression initiates when tumour cells separate from the primary tumour and insert into the bloodstream or the lymph system via intravasation. [2]

  3. Central nervous system prophylaxis - Wikipedia

    en.wikipedia.org/wiki/Central_nervous_system...

    Central Nervous System Prophylaxis, or CNS prophylaxis, is a type of chemotherapy for patients at risk of cancer metastasis into the central nervous system (CNS). [1] Prophylaxis originated from the Greek word “phulaxis”, meaning the act of guarding. [ 2 ]

  4. Central nervous system tumor - Wikipedia

    en.wikipedia.org/wiki/Central_nervous_system_tumor

    A central nervous system tumor (CNS tumor) is an abnormal growth of cells from the tissues of the brain or spinal cord. [1] CNS tumor is a generic term encompassing over 120 distinct tumor types. [2] Common symptoms of CNS tumors include vomiting, headache, changes in vision, nausea, and seizures. [3]

  5. Central nervous system effects from radiation exposure during ...

    en.wikipedia.org/wiki/Central_nervous_system...

    Although the unit mGy-Eq is used, the RBE for CNS effects is largely unknown; therefore, the use of the quality factor function for cancer risk estimates is advocated. For particles with charge Z>10, an addition PEL requirement limits the physical dose (mGy) for 1 year and the career to 100 and 250 mGy, respectively.

  6. Carmustine - Wikipedia

    en.wikipedia.org/wiki/Carmustine

    Carmustine is used as an alkylating agent to treat several types of brain cancer including glioma, glioblastoma multiforme, medulloblastoma and astrocytoma, multiple myeloma, and lymphoma (Hodgkin's and non-Hodgkin). Carmustine is sometimes used in conjunction with alkyl guanine transferase (AGT) inhibitors, such as O 6-benzylguanine.

  7. Decitabine/cedazuridine - Wikipedia

    en.wikipedia.org/wiki/Decitabine/cedazuridine

    Decitabine/cedazuridine is indicated for treatment of adults with myelodysplastic syndromes, including previously treated and untreated, de novo and secondary myelodysplastic syndromes with the following French American-British subtypes (refractory anemia, refractory anemia with ringed sideroblasts, refractory anemia with excess blasts, and chronic myelomonocytic leukemia) and intermediate-1 ...

  8. Hydromorphone - Wikipedia

    en.wikipedia.org/wiki/Hydromorphone

    Hydromorphone, also known as dihydromorphinone, and sold under the brand name Dilaudid among others, is a morphinan opioid used to treat moderate to severe pain. [7] Typically, long-term use is only recommended for pain due to cancer. [9] It may be used by mouth or by injection into a vein, muscle, or under the skin. [7]

  9. Tumor necrosis factor receptor 2 - Wikipedia

    en.wikipedia.org/wiki/Tumor_necrosis_factor...

    The protein encoded by this gene is a member of the tumor necrosis factor receptor superfamily, which also contains TNFRSF1A.This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity.