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Multiple sclerosis is typically diagnosed based on the presenting signs and symptoms, in combination with supporting medical imaging and laboratory testing. [4] It can be difficult to confirm, especially early on, since the signs and symptoms may be similar to those of other medical problems.
The McDonald criteria maintained a scheme for diagnosing MS based solely on clinical grounds but also proposed for the first time that when clinical evidence is lacking, magnetic resonance imaging (MRI) findings can serve as surrogates for dissemination in space (DIS) and/or time (DIT) to diagnose MS. [5] The criteria try to prove the existence ...
Diagnosis of MS has always been made by clinical examination, supported by MRI or CSF tests. According with both the pure autoimmune hypothesis and the immune-mediated hypothesis, [5] researchers expect to find biomarkers able to yield a better diagnosis, and able to predict the response to the different available treatments. [6]
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For each of the four type of MS, early diagnosis and treatment are key to slowing its progression. Skip to main content. 24/7 Help. For premium support please call: 800-290-4726 ...
What are the early signs of MS? Common symptoms of MS include the following: Fatigue. Walking gait difficulties. Muscle stiffness. Vision issues. Vertigo and dizziness. Sexual dysfunction. Bowel ...
Historically, the first widespread set of criteria were the Schumacher criteria (also spelled sometimes Schumacker). Currently, testing of cerebrospinal fluid obtained from a lumbar puncture can provide evidence of chronic inflammation of the central nervous system, looking for oligoclonal bands of IgG on electrophoresis, which are inflammation markers found in 75–85% of people with MS., [2 ...
Multiple sclerosis is typically diagnosed based on the presenting signs and symptoms, in combination with supporting medical imaging and laboratory testing. [5] It can be difficult to confirm, especially early on, since the signs and symptoms may be similar to those of other medical problems.
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