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severe pain; warmth; swelling of one or more joints; severe fatigue; fever; feeling of malaise or flu-like symptoms; inability to walk or perform everyday tasks or hobbies; gnawing/chewing sensations in the joints; burning; The symptoms can be monoarticular (involving a single joint) or polyarticular (involving several joints). [1]
A 2021 review found that hydroxychloroquine (HCQ) had no benefit in reducing pain and improving physical function in hand or knee osteoarthritis, and the off-label use of HCQ for people with osteoarthritis should be discouraged. [173] There is no evidence for the use of colchicine for treating the pain of hand or knee arthritis. [174]
The treatments may include joint replacement surgery for severely damaged joints, immunosuppressants for immune system dysfunction, antibiotics when an infection is the cause, and discontinuing medication when an allergic reaction is the cause. When treating the primary cause, pain management may still play a role in treatment. [15]
Arthritis is a general medical term used to describe a disorder that affects joints. [2] Symptoms generally include joint pain and stiffness. [2] Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. [2] [3] In certain types of arthritis, other organs such as the skin are also affected. [5]
The joints may also make sounds because of damage to or irregularity in the joint surface or internal structure of the joint, says Lawrie. People with arthritis usually experience this type of ...
Excessive growth of irritated synovial membrane causes it to increase its surface area by buckling into fronds, and the fronds may become inflamed and pour destructive enzymes into the joint space, causing joint swelling and joint surface destruction. Removing this excess material via lavage frequently resolves arthritic knee inflammation or pain.
Heterotopic ossification of varying severity can be caused by surgery or trauma to the hips and legs. About every third patient who has total hip arthroplasty (joint replacement) or a severe fracture of the long bones of the lower leg will develop heterotopic ossification, but is uncommonly symptomatic.
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