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2. Alcohol withdrawal syndrome - Wikipedia

   en.wikipedia.org/wiki/Alcohol_withdrawal_syndrome

   During acute alcohol withdrawal, changes also occur such as upregulation of alpha4 containing GABA A receptors and downregulation of alpha1 and alpha3 containing GABA A receptors. Neurochemical changes occurring during alcohol withdrawal can be minimized with drugs which are used for acute detoxification.

3. Alcohol-related brain damage - Wikipedia

   en.wikipedia.org/wiki/Alcohol-related_brain_damage

   Alcohol-related brain damage [1] [2] alters both the structure and function of the brain as a result of the direct neurotoxic effects of alcohol intoxication or acute alcohol withdrawal. Increased alcohol intake is associated with damage to brain regions including the frontal lobe , [ 3 ] limbic system , and cerebellum , [ 4 ] with widespread ...

4. What Really Happens to Your Body a Week After You Stop ... - AOL

   www.aol.com/really-happens-body-week-stop...

   One study found that even moderate alcohol consumption can cause changes to the brain’s structure, leading to cognitive decline in areas associated with memory and reasoning. In the study, more ...

5. Long-term impact of alcohol on the brain - Wikipedia

   en.wikipedia.org/wiki/Long-term_impact_of...

   Alcohol consumption can substantially impair neurobiologically-beneficial and -demanding exercise. [25] Long-term, stable consequences of chronic hazardous alcohol use are thought to be due to stable alterations of gene expression resulting from epigenetic changes within particular regions of the brain.

6. Kindling (sedative–hypnotic withdrawal) - Wikipedia

   en.wikipedia.org/wiki/Kindling_(sedative...

   The changes which occur after withdrawal in AMPA receptors in animals have been found in regions of the brain which govern anxiety and seizure threshold; thus kindling may result in increased severity of anxiety and a lowered seizure threshold during repeated withdrawal. Changes in the glutamate system and GABA system may play an important role ...

7. Delirium tremens - Wikipedia

   en.wikipedia.org/wiki/Delirium_tremens

   Delirium tremens is a component of alcohol withdrawal hypothesized to be the result of compensatory changes in response to chronic heavy alcohol use. Alcohol positively allosterically modulates the binding of GABA, enhancing its effect and resulting in inhibition of neurons projecting into the nucleus accumbens, as well as inhibiting NMDA ...

8. It's hard to stop at 1 drink. Here's why — and how to cut ...

   www.aol.com/lifestyle/hard-stop-1-drink-heres...

   Also, pay attention to any positive changes in your physical, emotional — even financial — health, such as experiencing better sleep or having more money in the bank. ... “Each year, alcohol ...

9. Alcoholic polyneuropathy - Wikipedia

   en.wikipedia.org/wiki/Alcoholic_polyneuropathy

   Total recorded alcohol consumption per capita of individuals 15 years or older, in liters of pure alcohol. Alcoholism is the main cause of alcoholic polyneuropathy. In 2020 the NIH quoted an estimate that in the United States 25% to 66% of chronic alcohol users experience some form of neuropathy. [7]