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The program's most notable contribution to HIV/AIDS medical research was the RV 144 vaccine study of over 16,000 volunteers in Thailand. In September 2009, the MHRP and the Thai Ministry of Health conducted the first successful HIV/AIDS vaccine trial to show effective prevention in humans, with a final prevention rate of 31%.
An HIV vaccine is a potential vaccine that could be either a preventive vaccine or a therapeutic vaccine, which means it would either protect individuals from being infected with HIV or treat HIV-infected individuals. It is thought that an HIV vaccine could either induce an immune response against HIV (active vaccination approach) or consist of ...
The International AIDS Vaccine Initiative (IAVI) is a global not-for-profit, public-private partnership working to accelerate the development of vaccines to prevent HIV infection and AIDS. IAVI researches and develops vaccine candidates, conducts policy analyses , serves as an advocate for the HIV prevention field and engages communities in the ...
Various approaches for HIV vaccine development. As of 2020, no effective vaccine for HIV or AIDS is known. [61] A single trial of the vaccine RV 144 found a partial efficacy rate around 30% and has stimulated optimism in the research community regarding developing a truly effective vaccine. [62] Further trials of the vaccine are ongoing. [63] [64]
AIDSVAX is an experimental HIV vaccine that was developed originally at Genentech in San Francisco, California, and later tested by the VaxGen company, a Genentech offshoot. [1] The development and trials of the vaccine received significant coverage in the international media, but American trials proved inconclusive.
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HIV/AIDS is a terminal illness, as there is currently no cure, nor an effective HIV vaccine. Treatment consists of highly active antiretroviral therapy (ART), which slows progression of the disease. [153] As of 2022, 39 million people globally were living with HIV, and 29.8 million people were accessing ART. [154]
It is the largest source of funding for HIV/AIDS within the United Nations system and has a portfolio of HIV/AIDS programmes dating back to 1989. [3] In 2000, the Bank launched the first phase of its response to HIV/AIDS in Sub-Saharan Africa – the Multi-Country AIDS Program (MAP).