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Avascular necrosis(AVN), also called osteonecrosisor bone infarction, is deathof bone tissue due to interruption of the blood supply.[1] Early on, there may be no symptoms.[1] Gradually joint painmay develop, which may limit the person's ability to move.[1] Complications may include collapse of the bone or nearby jointsurface.
James Paget. Paget's disease of bone (commonly known as Paget's disease or, historically, osteitis deformans) is a condition involving cellular remodeling and deformity of one or more bones. The affected bones show signs of dysregulated bone remodeling at the microscopic level, specifically excessive bone breakdown and subsequent disorganized ...
It is breakdown of the lunate bone, a carpal bone in the wrist that articulates with the radius in the forearm. Specifically, Kienböck's disease is another name for avascular necrosis [2] (death and fracture of bone tissue due to interruption of blood supply) with fragmentation and collapse of the lunate. This has classically been attributed ...
Osteonecrosis of the jaw (ONJ) is a severe bone disease (osteonecrosis) that affects the jaws (the maxilla and the mandible). Various forms of ONJ have been described since 1861, and a number of causes have been suggested in the literature. Osteonecrosis of the jaw associated with bisphosphonate therapy, which is required by some cancer ...
Bone marrow is a semi-solid tissue found within the spongy (also known as cancellous) portions of bones. [ 2 ] In birds and mammals, bone marrow is the primary site of new blood cell production (or haematopoiesis). [ 3 ] It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal cells.
The papillary dermis consists of loose connective tissue. Loose connective tissue, also known as areolar tissue, is a cellular connective tissue with thin and relatively sparse collagen fibers. They have a semi-fluid matrix with lesser proportions of fibers. Its ground substance occupies more volume than the fibers do.
Stromal cells can become connective tissue cells of any organ, for example in the uterine mucosa (endometrium), prostate, bone marrow, lymph node and the ovary. They are cells that support the function of the parenchymal cells of that organ. The most common stromal cells include fibroblasts and pericytes.
Anatomical terminology. [ edit on Wikidata] Diagram of a typical long bone showing both cortical (compact) and cancellous (spongy) bone. Haversian canals[ i ] (sometimes canals of Havers, osteonic canals or central canals) are a series of microscopic tubes in the outermost region of bone called cortical bone. They allow blood vessels and nerves ...